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成人颈椎髓内畸胎瘤

Intramedullary cervical teratoma in an adult.

作者信息

Arvin Babak, Pohl Ute, David Karoly

机构信息

Department of Neurosurgery, Queen's Hospital, Rom Valley Way, Romford Essex, London RM7 0AG, UK.

出版信息

Spine J. 2009 May;9(5):e14-8. doi: 10.1016/j.spinee.2008.09.001. Epub 2008 Dec 6.

DOI:10.1016/j.spinee.2008.09.001
PMID:19059809
Abstract

BACKGROUND AND CONTEXT

Mature teratomas are extremely rare spinal tumors, and in the cervical spine presentation in an adult it is even more infrequent. To the best of our knowledge, only five previous intramedullary teratomas in an adult cervical spine have been reported.

PURPOSE

Here, we present another case of a cervical intramedullary mature teratoma in an adult and review the literature.

STUDY DESIGN AND SETTING

Case report and review of the literature.

PATIENT SAMPLE

Thirty-four-year old man with initial symptoms of numbness of his left fingers, and later brachialgia of the whole arm. The diagnosis from initial manifestation of symptoms was relatively long (11 years).

METHOD

Case review and Medline/Internet search using key word adult, teratoma, cervical spine, and intramedullary.

RESULT

Case report presented. Only five cases of intramedullary cervical teratoma were found in the world literature.

CONCLUSION

Cervical intramedullary teratomas in adults are rare entities. The indolent nature of the condition often leads to late presentation. Surgery can result in good outcome and complete cure. This is, to our knowledge, only the sixth case of cervical teratoma in an adult.

摘要

背景与情境

成熟畸胎瘤是极为罕见的脊柱肿瘤,在成人颈椎中出现的情况更为罕见。据我们所知,此前仅报道过5例成人颈椎髓内畸胎瘤。

目的

在此,我们报告另一例成人颈椎髓内成熟畸胎瘤病例并复习相关文献。

研究设计与背景

病例报告及文献复习。

患者样本

一名34岁男性,最初症状为左手手指麻木,随后发展为全臂臂痛。从症状最初出现到确诊历时较长(11年)。

方法

病例复习,并通过医学在线数据库/互联网以“成人”“畸胎瘤”“颈椎”和“髓内”为关键词进行检索。

结果

呈现病例报告。在世界文献中仅发现5例颈椎髓内畸胎瘤病例。

结论

成人颈椎髓内畸胎瘤实属罕见。该病进展缓慢的特性常导致就诊延迟。手术可带来良好疗效并实现完全治愈。据我们所知,这是成人颈椎畸胎瘤的第6例病例。

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1
Intramedullary cervical teratoma in an adult.成人颈椎髓内畸胎瘤
Spine J. 2009 May;9(5):e14-8. doi: 10.1016/j.spinee.2008.09.001. Epub 2008 Dec 6.
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Acta Orthop Traumatol Turc. 2025 Apr 29;59(2):129-132. doi: 10.5152/j.aott.2025.24039.
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Adult-onset intramedullary teratomas: systematic review with outcome analysis.成人起病的髓内畸胎瘤:基于结局分析的系统评价
Acta Neurol Belg. 2025 Apr;125(2):319-334. doi: 10.1007/s13760-024-02667-x. Epub 2024 Oct 22.
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Effect of surgical resection extent on neurological prognosis of adult intradural spinal teratomas.
手术切除范围对成人硬脊膜内椎管内脊索瘤神经预后的影响。
Acta Neurochir (Wien). 2024 Oct 19;166(1):418. doi: 10.1007/s00701-024-06314-5.
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Mature Teratoma at the Lumbar Spinal Cord: A Case Report and Literature Review.腰椎脊髓成熟性畸胎瘤:一例报告及文献复习
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Medicine (Baltimore). 2020 May;99(18):e20107. doi: 10.1097/MD.0000000000020107.
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Eur Spine J. 2020 Feb;29(2):221-237. doi: 10.1007/s00586-019-06037-7. Epub 2019 Jun 21.
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J Neurosci Rural Pract. 2018 Oct-Dec;9(4):631-635. doi: 10.4103/jnrp.jnrp_30_18.
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Adult-onset intradural spinal teratoma: report of 18 consecutive cases and outcomes in a single center.成人起病的硬脊膜内脊髓畸胎瘤:单中心18例连续病例报告及预后分析
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