Van Dedem G, Moo-Young M
Biotechnol Bioeng. 1975 Sep;17(9):1301-12. doi: 10.1002/bit.260170905.
A model is developed to predict batch and continuous culture behavior of fermentations on two different carbon and energy sources. The basic assumption of the model is that the permease for the favored substrate is constitutive, whereas the premease for the second substrate is subject to induction and catabolite repression. Simulations of the model show features of diauxic growth described in the literature.
开发了一个模型来预测在两种不同碳源和能源上发酵的分批培养和连续培养行为。该模型的基本假设是,对首选底物的通透酶是组成型的,而对第二种底物的通透酶则受诱导和分解代谢物阻遏的影响。该模型的模拟显示了文献中描述的二次生长特征。