Grundsell H, Håkansson L, Owman C, Rosengren E, Sjöberg N O
Fertil Steril. 1975 Sep;26(9):919-23. doi: 10.1016/s0015-0282(16)41359-2.
An intrauterine device (IUD) consisting of either a plain or a copper-coated polyethylene catheter was inserted in one of the uteri of rabbits. Sham-operated uteri served as controls. The norepinephrine (NE) content was compared only between uteri within the same animal. Both copper and plastic IUDs markedly reduced the NE content in the uterus, but not in the oviduct, within 1 week after insertion. NE in both organs was present exclusively in the adrenergic nerve system. There was no difference in the action of the two types of IUDs. The effect of an IUD was probably eliminated by interruption of the preganglionic nerve connections. The results showed that the uterine adrenergic neurons are influenced by the presence of an IUD.
将由普通或铜包被的聚乙烯导管组成的宫内节育器（IUD）插入兔的一侧子宫内。假手术的子宫作为对照。仅比较同一动物体内子宫之间的去甲肾上腺素（NE）含量。在插入后1周内，铜质和塑料IUD均显著降低了子宫内的NE含量，但未降低输卵管内的NE含量。两个器官中的NE仅存在于肾上腺素能神经系统中。两种类型的IUD的作用没有差异。IUD的作用可能通过节前神经连接的中断而消除。结果表明，子宫肾上腺素能神经元受IUD存在的影响。
