Lin Fu-Wen, Wang Jhi-Joung, Wu Tian-Shung
Department of Chemistry, National Cheng Kung University, Tainan, Taiwan, ROC.
Chem Pharm Bull (Tokyo). 2002 Feb;50(2):157-9. doi: 10.1248/cpb.50.157.
Three new pavine N-oxide alkaloids, (-)-isocaryachine-N-oxide B, (+)-caryachine-N-oxide, (-)-caryachine-N-oxide, and a new isoquinoline alkaloid, 6,7-methylenedioxy-N-methylisoquinoline together with 11 known alkaloids were isolated and characterized from the stem bark of Cryptocarya chinensis. The structures of the isolated compounds were determined by spectral methods. The stereochemistry of pavine-N-oxide alkaloids is also discussed.
从中国厚壳桂的茎皮中分离并鉴定出三种新的阿朴啡N-氧化物生物碱，即(-)-异卡里阿钦-N-氧化物B、(+)-卡里阿钦-N-氧化物、(-)-卡里阿钦-N-氧化物，以及一种新的异喹啉生物碱6,7-亚甲二氧基-N-甲基异喹啉，同时还分离出11种已知生物碱。通过光谱方法确定了分离出的化合物的结构。还讨论了阿朴啡-N-氧化物生物碱的立体化学。
