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缺氧幼犬胃肠道的微循环变化:一项电子显微镜研究

Microcirculatory changes in the gastrointestinal tract of the hypoxic puppy: an electron microscope study.

作者信息

Harrison M W, Connell R S, Campbell J R, Webb M C

出版信息

J Pediatr Surg. 1975 Oct;10(5):599-608. doi: 10.1016/0022-3468(75)90362-0.

DOI:10.1016/0022-3468(75)90362-0
PMID:1185449
Abstract

Hypoxia and hypovolemia result in similar ultrastructural changes. These changes are characterized by aggregation of platelets and leukocytes in the vascular space, focal endothelial cell disruption, and appearance of increased amounts of perivascular edema, and loss of ultrastructural organization of the mucosal cell. These changes appear to relate to variations in blood flow to the mucosa of different areas of the bowel and to follow the distribution observed for necrotizing enterocolitis in the human infant.

摘要

缺氧和低血容量会导致相似的超微结构变化。这些变化的特征是血管腔内血小板和白细胞聚集、局灶性内皮细胞破坏、血管周围水肿增加以及黏膜细胞超微结构组织的丧失。这些变化似乎与肠道不同区域黏膜血流的变化有关,并与人类婴儿坏死性小肠结肠炎的分布情况一致。

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Microcirculatory changes in the gastrointestinal tract of the hypoxic puppy: an electron microscope study.缺氧幼犬胃肠道的微循环变化:一项电子显微镜研究
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引用本文的文献

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State-of-the-art review and update of models of necrotizing enterocolitis.坏死性小肠结肠炎模型的最新综述与更新
Front Pediatr. 2023 Apr 4;11:1161342. doi: 10.3389/fped.2023.1161342. eCollection 2023.
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Pediatr Surg Int. 2006 Sep;22(9):719-23. doi: 10.1007/s00383-006-1728-2. Epub 2006 Jul 27.
3
Necrotizing enterocolitis: a continuing problem in the neonate.
坏死性小肠结肠炎:新生儿中持续存在的问题。
World J Surg. 1993 May-Jun;17(3):363-73. doi: 10.1007/BF01658705.
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Neonatal gastric perforations; a diagnostic clue in pre-perforative phase.新生儿胃穿孔;穿孔前期的诊断线索
Jpn J Surg. 1983 Sep;13(5):446-51. doi: 10.1007/BF02469734.
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Perinatal risk factors for necrotizing enterocolitis.坏死性小肠结肠炎的围产期危险因素。
Arch Dis Child. 1984 May;59(5):430-4. doi: 10.1136/adc.59.5.430.
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Stress-induced disturbances of the gastro-intestinal tract in children.儿童应激诱发的胃肠道紊乱
Intensive Care Med. 1989;15 Suppl 1:S32-6. doi: 10.1007/BF00260881.
7
Microcirculatory changes in the lung of the hypoxic and hypovolemic puppy: an electron microscope study.低氧血症和低血容量幼犬肺部的微循环变化:一项电子显微镜研究。
Ann Surg. 1977 Mar;185(3):311-7. doi: 10.1097/00000658-197703000-00011.
8
Surgical experience with neonatal necrotizing enterocolitis (NNE).新生儿坏死性小肠结肠炎(NNE)的手术经验。
Ann Surg. 1979 May;189(5):612-9. doi: 10.1097/00000658-197905000-00011.