Grünhagen Dirk J, de Boer Mark G J, de Beaufort Arnout Jan, Walther Frans J
Department of Pediatrics, Division of Neonatology, Leiden University Medical Center and Juliana Children's Hospital, Leiden/The Hague, The Netherlands.
Pediatr Res. 2002 Mar;51(3):402-5. doi: 10.1203/00006450-200203000-00022.
Among preterm infants there is a relationship between skin blood flow and transepidermal water loss (TEWL). The aim of this study was to assess whether halogen spotlight phototherapy without significant heat stress increases TEWL and affects maintenance fluid requirements in preterm infants. TEWL was measured noninvasively before the start and after 1 h of halogen spotlight phototherapy in a group of preterm infants, nursed in double-walled incubators with moderately high relative humidity. Relative humidity and ambient temperature in the incubator were tightly controlled. Mean +/- SD birth weight of the 18 infants was 1412 +/- 256 g, gestational age 30.6 +/- 1.6 wk, and age at measurement 5 +/- 3 d. Nine infants received ventilatory assistance. Relative humidity was 40-80% (mean 52%). Average TEWL increased from 13.6 to 16.5 g/m(2)/h during phototherapy. These data show that TEWL increases by approximately 20% during phototherapy despite constant skin temperature and relative humidity. Maintenance fluids of preterm infants should be increased by 0.35 mL/kg/h during exposure to halogen spotlight phototherapy.
在早产儿中,皮肤血流量与经表皮水分流失(TEWL)之间存在关联。本研究的目的是评估无明显热应激的卤素聚光灯光疗是否会增加TEWL并影响早产儿的维持液需求量。在一组置于相对湿度适中的双壁暖箱中护理的早产儿中,于卤素聚光灯光疗开始前及开始1小时后对TEWL进行无创测量。暖箱内的相对湿度和环境温度得到严格控制。18名婴儿的平均出生体重±标准差为1412±256克,胎龄30.6±1.6周,测量时年龄5±3天。9名婴儿接受通气辅助。相对湿度为40 - 80%(平均52%)。光疗期间平均TEWL从13.6克/平方米/小时增加至16.5克/平方米/小时。这些数据表明,尽管皮肤温度和相对湿度恒定,但光疗期间TEWL仍增加约20%。在早产儿接受卤素聚光灯光疗期间,维持液量应增加0.35毫升/千克/小时。