Lock G
Department of Internal Medicine I, University of Regensburg, D-93042 Regensburg, Germany.
Best Pract Res Clin Gastroenterol. 2001 Dec;15(6):919-41. doi: 10.1053/bega.2001.0250.
In the 1960s, the term 'presbyoesophagus' was introduced for what were felt to be the characteristics of the oesophagus in old age. Since then a number of sophisticated studies using modern manometric, radiological, pH-metric or endoscopic equipment have been performed to better study this subject. Although results in some aspects are still contradictory, these studies have provided us with some more detailed information on the physiology of the ageing oesophagus. Beginning with an overview of what is currently known and discussed about age-induced physiological changes in oesophageal function, this review will then focus on specific problems of oesophagus-related diseases in the elderly. The main topics discussed will include presentation, diagnosis and treatment of primary and secondary motility disorders, oesophageal manifestations of neuromuscular and neurological disease, gastro-oesophageal reflux disease and oesophageal cancer in the elderly.
20世纪60年代，“老年食管”一词被用来描述人们所认为的老年食管的特征。从那时起，人们进行了一系列使用现代测压、放射学、pH测量或内镜设备的复杂研究，以更好地研究这个课题。尽管某些方面的结果仍存在矛盾，但这些研究为我们提供了一些关于衰老食管生理学的更详细信息。本文首先概述目前已知和讨论的食管功能随年龄增长而发生的生理变化，然后将重点关注老年人食管相关疾病的具体问题。讨论的主要主题将包括原发性和继发性动力障碍的表现、诊断和治疗，神经肌肉和神经系统疾病的食管表现，老年人的胃食管反流病和食管癌。
