Margolis Karen L, Kerani Roxanne Pieper, McGovern Paul, Songer Thomas, Cauley Jane A, Ensrud Kristine E
Division of Clinical Epidemiology, Hennepin County Medical Center, Minneapolis, Minnesota 55415, USA.
J Gerontol A Biol Sci Med Sci. 2002 Mar;57(3):M186-91. doi: 10.1093/gerona/57.3.m186.
Motor vehicle crash and fatality rates are higher per mile driven for elderly drivers, with an exponential increase above age 75. Identifying elderly drivers who are at risk for automobile crashes may help direct interventions to reduce their high rate of injuries and deaths.
Subjects were 1416 women aged 65 to 84 enrolled in the Portland, Ore. site of the Study of Osteoporotic Fractures. Motor vehicle crash information for the years 1986-1995 for each participant was obtained from the Oregon State Department of Transportation. Items from questionnaires, interviews, and physical examinations were tested prospectively for associations with the occurrence of motor vehicle crashes.
About one third of participants (415 of 1416) had a motor vehicle crash during a mean follow-up time of 5.7 years. After adjustment for age and weekly driving mileage, risk factors significantly associated with motor vehicle crashes were a fall in the previous year [hazard ratio (HR) 1.53, 95% confidence interval (CI) 1.26-1.86], a greater orthostatic systolic blood pressure drop (HR 1.11 per 12.5 mm Hg, 95% CI 1.01-1.22), and increased foot reaction time (HR 1.10 per 0.06 second, 95% CI 1.00-1.22). Other neuromuscular tests, functional status, medical diagnoses, vision tests, and cognitive tests did not predict motor vehicle crashes in this study population.
This prospective study with extended follow-up of a large cohort of elderly women has identified crash risk factors that can be measured in the clinical setting. Further study is needed to determine if interventions aimed at these risk factors can decrease the risk of motor vehicle crashes.
每行驶一英里,老年驾驶员的机动车碰撞事故率和死亡率更高,75岁以上呈指数级增长。识别有机动车碰撞风险的老年驾驶员可能有助于指导干预措施,以降低他们的高伤亡率。
研究对象为1416名年龄在65至84岁之间、参与俄勒冈州波特兰市骨质疏松性骨折研究的女性。每位参与者1986 - 1995年的机动车碰撞事故信息来自俄勒冈州运输部。对问卷、访谈和体格检查中的项目进行前瞻性测试,以确定其与机动车碰撞事故发生之间的关联。
在平均5.7年的随访期内,约三分之一的参与者(1416名中的415名)发生了机动车碰撞事故。在调整年龄和每周驾驶里程后,与机动车碰撞事故显著相关的风险因素包括:前一年跌倒(风险比[HR] 1.53,95%置信区间[CI] 1.26 - 1.86)、直立性收缩压下降幅度更大(每12.5毫米汞柱HR 1.11,95% CI 1.01 - 1.22)以及足部反应时间增加(每0.06秒HR 1.10,95% CI 1.00 - 1.22)。在该研究人群中,其他神经肌肉测试、功能状态、医学诊断、视力测试和认知测试均不能预测机动车碰撞事故。
这项对大量老年女性队列进行长期随访的前瞻性研究确定了可在临床环境中测量的碰撞风险因素。需要进一步研究以确定针对这些风险因素的干预措施是否能降低机动车碰撞事故的风险。