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拉贝洛尔在全科医疗中的长期研究。

A long-term study of labetalol in general practice.

作者信息

Kane J, Gregg I, Stephens M D

出版信息

Br J Clin Pharmacol. 1979;8(Suppl 2):167S-170S.

Abstract

1 Forty-one patients with mild to moderate hypertension have been treated with labetalol for up to 5 years. 2 Mean BP before treatment was 180/107 mm Hg, after 2--3 yr treatment was 136/81 mmHg and after 5 yr was 136/74 mmHg. 3 One patient developed a licheniform rash and two patients have died of myocardial infarction. No other side-effects, not already observed in a previously reported double-blind trial, have emerged.

摘要
  1. 41例轻至中度高血压患者接受了拉贝洛尔治疗,最长达5年。2. 治疗前平均血压为180/107 mmHg,治疗2至3年后为136/81 mmHg,5年后为136/74 mmHg。3. 1例患者出现苔藓样皮疹,2例患者死于心肌梗死。未出现之前报道的双盲试验中未观察到的其他副作用。

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Double-blind trial of labetalol.拉贝洛尔双盲试验。
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Labetalol in general practice: a review.拉贝洛尔在全科医疗中的应用:综述
Br J Clin Pharmacol. 1982 Jun;13(1 Suppl):59S-63S. doi: 10.1111/j.1365-2125.1982.tb01890.x.
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Pharmacology of combined alpha-beta-blockade. I.α-β联合阻滞的药理学。I.
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本文引用的文献

4
Double-blind trial of labetalol.拉贝洛尔双盲试验。
Br J Clin Pharmacol. 1976 Aug;3(4 Suppl 3):737-41.
6
Bullous lichen planus caused by labetalol.拉贝洛尔所致大疱性扁平苔藓。
Br Med J. 1978 Apr 1;1(6116):816-7. doi: 10.1136/bmj.1.6116.816-a.

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