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拉贝洛尔对高血压的长期治疗作用。

Long-term treatment of hypertension with labetalol.

作者信息

Prichard B N, Boakes A J, Hernández R

出版信息

Br J Clin Pharmacol. 1979;8(Suppl 2):171S-177S.

Abstract

1 Thirty-two hypertensive patients have been treated with labetalol for periods of up to 7 years. 2 Ten patients observed for 6 years from time of stabilization of dosage, did not show any tolerance to labetalol. 3 Postural and exercise hypotension were not seen in these patients over this prolonged follow-up, although they were seen in other patients given over 2 g labetalol daily.

摘要
  1. 32例高血压患者接受了拉贝洛尔治疗,治疗时间长达7年。2. 10例患者自剂量稳定起观察了6年,未表现出对拉贝洛尔的任何耐受性。3. 在这一长期随访过程中,这些患者未出现体位性和运动性低血压,尽管在其他每日服用超过2g拉贝洛尔的患者中观察到了这种情况。

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2
Labetalol steady-state pharmacokinetics in hypertensive patients.高血压患者中拉贝洛尔的稳态药代动力学
Br J Clin Pharmacol. 1982 Jun;13(1 Suppl):75S-80S. doi: 10.1111/j.1365-2125.1982.tb01892.x.
3
Rapid reduction of blood pressure with acute oral labetalol.急性口服拉贝洛尔使血压迅速降低。
Br J Clin Pharmacol. 1982 May;13(5):705-10. doi: 10.1111/j.1365-2125.1982.tb01440.x.
6
Comparison of labetalol with other anti-hypertensive drugs.拉贝洛尔与其他抗高血压药物的比较。
Br J Clin Pharmacol. 1982 Jun;13(1 Suppl):41S-47S. doi: 10.1111/j.1365-2125.1982.tb01888.x.

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