Sun B, He Y, Zhong P, Wang R
Henan Institute of Ophthalmology, Zhengzhou, 450003.
Zhonghua Yan Ke Za Zhi. 1998 Jan;34(1):31-3.
To report a rare type of corneal edema, i.e. peripheral corneal edema after cataract extraction---Brown-Mclean syndrome.
Clinical charts of 8 affected eyes in 5 patients were reviewed. Ultrasound pachymetry was used to determine central corneal thickness. Cell densities were measured by specular microscopy. The clinical characteristics and pathogenesis were discussed.
The average time from operation to initial diagnosis was 10.5 years. The typical edema started inferiorly and progressed circumferentially, but central portion of the cornea was clear. The corneal thickness at edematous area was increased. The cell counts of endothelium was decreased in our patients. Additionally, the edema was associated with a punctate orange-brown pigmentation on the endothelium.
So far this new syndrome of corneal edema has not been reported in china. Its clinical characteristics are not similar to that of conventional edema after intracapsular cataract extraction. The pathogenesis of this curious condition is still unknown. It may be associated with an aphakic eye, chronic uveitis and hereditary factors.
报告一种罕见的角膜水肿类型，即白内障摘除术后周边角膜水肿——布朗 - 麦克林综合征。
回顾了5例患者8只患眼的临床病历。采用超声角膜测厚法测定中央角膜厚度。通过镜面显微镜测量细胞密度。对临床特征和发病机制进行了讨论。
从手术到初步诊断的平均时间为10.5年。典型的水肿从下方开始并沿周边进展，但角膜中央部分清晰。水肿区域的角膜厚度增加。我们患者的内皮细胞计数减少。此外，水肿与内皮上的点状橙棕色色素沉着有关。
迄今为止，这种新的角膜水肿综合征在中国尚未见报道。其临床特征与传统的囊内白内障摘除术后水肿不同。这种奇特病症的发病机制仍然未知。它可能与无晶状体眼、慢性葡萄膜炎和遗传因素有关。
