Connor Daniel F, Glatt Stephen J, Lopez Ivan D, Jackson Denise, Melloni Richard H
Division of Child and Adolescent Psychiatry, University of Massachusetts Medical School, Worcester 01655, USA.
J Am Acad Child Adolesc Psychiatry. 2002 Mar;41(3):253-61. doi: 10.1097/00004583-200203000-00004.
To determine by meta-analysis the effect size for stimulants on overt and covert aggression-related behaviors in children with attention-deficit/hyperactivity disorder (ADHD), separately from stimulant effects on the core symptoms of ADHD.
A review of the literature from 1970 to 2001 revealed 28 studies meeting inclusion/exclusion criteria for meta-analysis. These studies yielded 28 independent effects of overt aggression and 7 independent effects of covert aggression.
The overall weighted mean effect size was 0.84 for overt and 0.69 for covert aggression related behaviors in ADHD. Comorbid conduct disorder is associated with diminishing stimulant effect size for overt aggression.
Stimulant effects for aggression-related behaviors in ADHD have effect sizes similar to those for the core symptoms of ADHD.
通过荟萃分析确定兴奋剂对注意力缺陷多动障碍（ADHD）儿童公开和隐蔽的攻击相关行为的效应量，与兴奋剂对ADHD核心症状的效应分开。
对1970年至2001年的文献进行回顾，发现28项研究符合荟萃分析的纳入/排除标准。这些研究产生了28个公开攻击的独立效应和7个隐蔽攻击的独立效应。
ADHD中公开攻击相关行为的总体加权平均效应量为0.84，隐蔽攻击相关行为为0.69。共患品行障碍与公开攻击的兴奋剂效应量降低有关。
兴奋剂对ADHD攻击相关行为的效应量与对ADHD核心症状的效应量相似。
