Desjardins Lisa A
Clin J Oncol Nurs. 2002 Mar-Apr;6(2):107-8. doi: 10.1188/02.CJON.107-108.
Hepatocellular carcinoma (HCC) is a common malignancy worldwide and is a disease of multifactorial etiology. Strong correlations exist between the prevalence of the hepatitis B and C viruses and HCC incidence. HCC treatment may involve surgical resection, liver transplantation, locoregional treatments, and chemotherapy. Prevention of virus-related HCC is contingent upon control of hepatitis types B and C. Universal vaccination against hepatitis B could eliminate hepatitis B-related HCC; however, hepatitis C-related HCC still could occur because a vaccine for hepatitis C currently is not available. Individuals at risk for HCC should be screened for the disease. Early detection could result in improved prognosis and survival.
肝细胞癌(HCC)是全球常见的恶性肿瘤,是一种病因多因素的疾病。乙型和丙型肝炎病毒的流行率与HCC发病率之间存在密切关联。HCC治疗可能包括手术切除、肝移植、局部区域治疗和化疗。预防病毒相关的HCC取决于对乙型和丙型肝炎的控制。普遍接种乙型肝炎疫苗可消除乙型肝炎相关的HCC;然而,丙型肝炎相关的HCC仍可能发生,因为目前尚无丙型肝炎疫苗。HCC高危个体应进行该疾病的筛查。早期检测可改善预后和生存率。