Nair Rashmi S, Fuchs Roy L, Schuette Sheila A
Monsanto Company, St Louis, Missouri 63167, USA.
Toxicol Pathol. 2002 Jan-Feb;30(1):117-25. doi: 10.1080/01926230252824806.
Several laboratories have used recombinant DNA technology in plant breeding to improve compositional, processing, and agronomic characteristics of plants. These transformed plants have been extensively tested in field trials, have gained full regulatory approvals and are currently being marketed in a number of countries around the world. This paper briefly summarizes the approach used to assure the safety of foods and feeds derived from these genetically modified crops, as exemplified by data on Roundup Ready soybeans that has been developed by Monsanto Company using biotechnology in order to confer tolerance to glyphosate, the active ingredient in Roundup herbicide, by the production of the CP4 enolpyruvylshikimate-3-phosphate synthase protein. The results of the studies demonstrate that Roundup Ready soybeans are as safe as traditional soybeans with respect to food and feed safety.
一些实验室已利用重组DNA技术进行植物育种，以改善植物的成分、加工特性和农艺性状。这些转基因植物已在田间试验中得到广泛测试，获得了全面的监管批准，目前正在世界多个国家上市销售。本文简要总结了确保这些转基因作物衍生的食品和饲料安全性所采用的方法，以孟山都公司利用生物技术培育的抗草甘膦大豆的数据为例，该技术通过生产CP4 5-烯醇丙酮酰莽草酸-3-磷酸合酶蛋白，使大豆对草甘膦除草剂中的活性成分草甘膦具有耐受性。研究结果表明，就食品和饲料安全性而言，抗草甘膦大豆与传统大豆一样安全。
