Mori Susumu, Frederiksen Kim, van Zijl Peter C M, Stieltjes Bram, Kraut Michael A, Solaiyappan Meiyappan, Pomper Martin G
Department of Radiology, Johns Hopkins University School of Medicine, F. M. Kirby Research Center, Kennedy Krieger Institute, Baltimore, MD 21205, USA.
Ann Neurol. 2002 Mar;51(3):377-80. doi: 10.1002/ana.10137.
We applied multislice, whole-brain diffusion tensor imaging (DTI) to two patients with anaplastic astrocytoma. Data were analyzed using DTI-based, color-coded images and a 3-D tract reconstruction technique for the study of altered white matter anatomy. Each tumor was near two major white matter tracts, namely, the superior longitudinal fasciculus and the corona radiata. Those tracts were identified using the color-coded maps, and spatial relationships with the tumors were characterized. In one patient the tumor displaced adjacent white matter tracts, whereas in the other it infiltrated the superior longitudinal fasciclus without displacement of white matter. DTI provides new information regarding the detailed relationship between tumor growth and nearby white matter tracts, which may be useful for preoperative planning.
我们对两名间变性星形细胞瘤患者应用了多层全脑扩散张量成像（DTI）。使用基于DTI的彩色编码图像和三维纤维束重建技术分析数据，以研究白质解剖结构的改变。每个肿瘤都靠近两条主要的白质束，即上纵束和放射冠。利用彩色编码图谱识别这些纤维束，并描述它们与肿瘤的空间关系。在一名患者中，肿瘤使相邻的白质束移位，而在另一名患者中，肿瘤浸润上纵束但未使白质移位。DTI提供了关于肿瘤生长与附近白质束之间详细关系的新信息，这可能有助于术前规划。
