Oğuz V, Yolar M, Yetik H, Cakirer D, Uysal O, Pazarli H
Service d'ophtalmologie, Unité de la biostatistique, faculté de médecine de cerrahpaşa, université d'lstanbul.
J Fr Ophtalmol. 2001 Oct;24(8):842-6.
In order to evaluate the predictability of the results in the treatment of myopathy in cases with the clinical signs of muscle involvement, 177 extraocular muscles of 27 cases whose oedematous status was detected by MRI and who were given antiinflammatory treatment according to the data of this method, were studied. The nature of involvement was detected in respect with the signal intensity and thickness of each rectus muscle prior to the treatment and at the end of the sixth month following a three months' application of combined treatment of steroids and irradiation of 2000 rads. When the initial and final results were compared, the signal intensities of four involved recti showed significant decrease at the end of the treatment, as they were evaluated separately or together. Besides the thicknesses of these groups of involved recti which were evaluated separately showed significant decrease. The evaluation of the signal intensities by MRI is a way that enables noninvasive detection of the edema and prediction of the anti-inflammatory treatment's results of dysthyroid myopathy. Therefore a systematic follow up by MRI is recommended for the treatment choice in dysthyroid myopathy.
为了评估在具有肌肉受累临床体征的病例中治疗肌病结果的可预测性，对27例通过MRI检测到水肿状态并根据该方法的数据接受抗炎治疗的患者的177条眼外肌进行了研究。在治疗前以及在应用2000拉德的类固醇和放射联合治疗三个月后的第六个月末，根据每条直肌的信号强度和厚度检测受累性质。当比较初始和最终结果时，四条受累直肌的信号强度在治疗结束时显示出显著下降，无论是单独评估还是一起评估。此外，这些单独评估的受累直肌组的厚度也显示出显著下降。通过MRI评估信号强度是一种能够无创检测水肿并预测甲状腺功能障碍性肌病抗炎治疗结果的方法。因此，建议对甲状腺功能障碍性肌病的治疗选择进行MRI系统随访。
