Lemons James, Fanaroff Avroy, Stewart Edward J, Bentkover Judith D, Murray Gail, Diefendorf Allan
Section of Neonatal-Perinatal Medicine, Riley Hospital for Children, Indianapolis, IN 46202-5119, USA.
J Perinatol. 2002 Mar;22(2):120-4. doi: 10.1038/sj.jp.7210618.
To evaluate the costs and performance characteristics associated with the start-up phase of Universal Newborn Hearing Screening Programs, one utilizing automated auditory brainstem response (AABR) and the other using transient evoked otoacoustic emissions (TEOAE).
Economic and performance data were collected at the initiation of both screening programs. Data were collected until 1500 newborn infants were screened or until a referral rate for further audiologic evaluation at hospital discharge of less than or equal to 5% was achieved. Data collected included screening pass/fail rates, referral rates and personnel, equipment, and supply utilization. Actual costs of personnel, equipment, and supplies were used. Statistical comparisons of proportions using z-statistic with the one-tailed test and an alpha of 0.01 were made.
Screening in the AABR program was performed by neonatal nurses, whereas screening in the TEOAE program was performed by master's level audiologists. The average age at initial screen was 29 hours for TEOAE, and 9.5 hours for AABR. Eighty-four percent of infants was screened within 24 hours in the AABR program, in contrast to 35% in the TEOAE program. Throughout the duration of the study, the referral rate at hospital discharge remained approximately 15% for the TEOAE program. The AABR referral rate began at 8% and was less than 4% at the completion of the study. Pre-discharge total costs for initiating and establishing the programs were US$49,316 for TEOAE and US$47,553 for AABR. Cost per infant screened was US$32.23 and US$33.68, respectively. When post-discharge screening and diagnostic evaluation costs were included, the total cost per infant screened was US$58.07 for TEOAE and US$45.85 for AABR.
AABR appears to be the preferred method for universal newborn hearing screening. AABR was associated with the lowest costs, achieved the lowest referral rates at hospital discharge, and had the quickest learning curve to achieve those rates.
评估通用新生儿听力筛查项目启动阶段的成本及性能特征,其中一个项目采用自动听性脑干反应(AABR),另一个项目采用瞬态诱发耳声发射(TEOAE)。
在两个筛查项目启动时收集经济和性能数据。持续收集数据,直至筛查1500名新生儿,或直至出院时进一步听力评估的转诊率小于或等于5%。收集的数据包括筛查通过/失败率、转诊率以及人员、设备和用品的使用情况。使用人员、设备和用品的实际成本。采用单尾检验的z统计量对比例进行统计比较,α值为0.01。
AABR项目的筛查由新生儿护士进行,而TEOAE项目的筛查由硕士水平的听力学家进行。TEOAE初始筛查的平均年龄为29小时,AABR为9.5小时。在AABR项目中,84%的婴儿在24小时内接受了筛查,而TEOAE项目中这一比例为35%。在整个研究期间,TEOAE项目出院时的转诊率约为15%。AABR转诊率开始时为8%,研究结束时低于4%。启动和建立项目的出院前总成本,TEOAE项目为49316美元,AABR项目为47553美元。每个筛查婴儿的成本分别为32.23美元和33.68美元。当纳入出院后筛查和诊断评估成本时,每个筛查婴儿的总成本,TEOAE项目为58.07美元,AABR项目为45.85美元。
AABR似乎是通用新生儿听力筛查的首选方法。AABR成本最低,出院时转诊率最低,且达到这些比率的学习曲线最快。