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采用瞬态诱发耳声发射(TEOAE)进行一步法听力筛查程序与采用TEOAE和自动听性脑干反应进行两步法听力筛查程序的比较。

Comparison of hearing screening programs between one step with transient evoked otoacoustic emissions (TEOAE) and two steps with TEOAE and automated auditory brainstem response.

作者信息

Lin Hung-Ching, Shu Min-Tsan, Lee Kuo-Sheng, Ho Guan-Min, Fu Tzu-Yu, Bruna Sharon, Lin Grace

机构信息

Department of Otolaryngology, Hearing and Speech Center, Mackay Memorial Hospital, Taipei, Taiwan.

出版信息

Laryngoscope. 2005 Nov;115(11):1957-62. doi: 10.1097/01.mlg.0000178323.06183.3e.

Abstract

OBJECTIVE

To compare the efficacy between one step with transient evoked otoacoustic emissions (TEOAE) and two steps with TEOAE and automated auditory brainstem response (AABR) in a newborn hearing screening program. We investigated their differences in referral rate, the accurate identification rate of congenital hearing loss (HL), and cost effectiveness.

METHOD

From November 1998 to December 2004, a total of 21,273 healthy newborns were screened for HL in Mackay Memorial Hospital, Taipei. In the periods from November 1998 to January 2004 and from February 2004 to December 2004, the screening tools used were TEOAE alone (n = 18,260) and TEOAE plus AABR (n = 3,013), respectively.

RESULTS

A statistically significant decrease of referral rate was achieved in the group using TEOAE and AABR as screening tools when compared with TEOAE alone (1.8% vs. 5.8%). The accurate identification rate of congenital HL was 0.45% in TEOAE protocol and 0.3% in TEOAE and AABR protocol, which was not statistically significant. The total direct costs per screening were 10.1 U.S. dollars for the program using TEOAE alone and 8.9 U.S. dollars for the TEOAE plus AABR program. The intangible cost, however, was much higher in the earlier program because of the higher referral rate.

CONCLUSION

In terms of the efficacy of a hearing screening program using the one step TEOAE and two step TEOAE and AABR programs, the later significantly decreased the referral rate from 5.8% to 1.8%. No significant difference was noted between the accurate identification rates of congenital HL. The total costs, including expenditures and intangible cost, were lower in the protocol with TEOAE plus AABR.

摘要

目的

比较在新生儿听力筛查项目中,采用瞬态诱发耳声发射(TEOAE)一步法与采用TEOAE和自动听性脑干反应(AABR)两步法的效果。我们研究了它们在转诊率、先天性听力损失(HL)准确识别率以及成本效益方面的差异。

方法

1998年11月至2004年12月,台北市马偕纪念医院对总共21273名健康新生儿进行了HL筛查。在1998年11月至2004年1月以及2004年2月至12月期间,分别使用的筛查工具为单独的TEOAE(n = 18260)和TEOAE加AABR(n = 3013)。

结果

与单独使用TEOAE相比,采用TEOAE和AABR作为筛查工具的组转诊率有统计学显著下降(1.8%对5.8%)。在TEOAE方案中先天性HL的准确识别率为0.45%,在TEOAE和AABR方案中为0.3%,无统计学显著差异。单独使用TEOAE的筛查项目每次筛查的总直接成本为10.1美元,TEOAE加AABR项目为8.9美元。然而,由于转诊率较高,早期项目的无形费用要高得多。

结论

就采用TEOAE一步法和TEOAE与AABR两步法的听力筛查项目效果而言,后者显著降低了转诊率,从5.8%降至1.8%。先天性HL的准确识别率之间无显著差异。包括支出和无形费用在内的总成本在TEOAE加AABR方案中更低。

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