Reyner L A, Horne J A
Sleep Research Centre, Loughborough University,Loughborough, Leicestershire LE11 3TU, UK.
Physiol Behav. 2002 Mar;75(3):331-5. doi: 10.1016/s0031-9384(01)00669-2.
Driver sleepiness is a major cause of serious road crashes. Coffee is often used as an effective countermeasure to driver sleepiness. However, the caffeine levels in coffee are variable, whereas certain proprietary "functional energy drinks" (FEDs) contain known levels of caffeine (and other ingredients). We investigated the effectiveness of a well-known FED in reducing sleepiness in drivers. Twelve healthy young adults drove an instrumented car simulator between 14:00 and 17:00 h. Their sleepiness was enhanced by sleep restriction to 5 h the night before. Following a pretreatment 30-min drive and at the beginning of a 30-min break, participants were given double-blind 250-ml FED (containing sucrose, glucose, 80-mg caffeine, taurine, glucuronolactone and vitamins) vs. a control drink with the same volume and same taste but without caffeine, taurine and glucuronolactone. Two hours of continuous driving ensued. Lane drifting, subjective sleepiness and the electroencephalogram (EEG) were monitored throughout. Compared with the control, the FED significantly reduced sleep-related driving incidents and subjective sleepiness for the first 90 min of the drive. There was a trend for the EEG to reflect less sleepiness during this period. It was concluded that the FED is beneficial in reducing sleepiness and sleep-related driving incidents under conditions of afternoon monotonous driving following sleep restriction the night before.
驾驶员困倦是严重道路交通事故的主要原因。咖啡常被用作应对驾驶员困倦的有效对策。然而,咖啡中的咖啡因含量各不相同,而某些专利“功能性能量饮料”(FED)含有已知含量的咖啡因(以及其他成分)。我们研究了一种知名FED在减轻驾驶员困倦方面的效果。12名健康的年轻成年人在14:00至17:00驾驶一辆配备仪器的汽车模拟器。前一晚将他们的睡眠时间限制在5小时,以增强他们的困倦感。在进行30分钟的预处理驾驶后以及在30分钟休息开始时,参与者被给予双盲的250毫升FED(含有蔗糖、葡萄糖、80毫克咖啡因、牛磺酸、葡萄糖醛酸内酯和维生素),与之对比的是一种体积和味道相同但不含咖啡因、牛磺酸和葡萄糖醛酸内酯的对照饮料。随后进行两小时的连续驾驶。在此期间全程监测车道偏移、主观困倦感和脑电图(EEG)。与对照组相比,FED在驾驶的前90分钟显著减少了与睡眠相关的驾驶事件和主观困倦感。在此期间脑电图有反映出困倦程度降低的趋势。研究得出结论,在前一晚睡眠受限的情况下,FED有利于减轻下午单调驾驶条件下的困倦感以及与睡眠相关的驾驶事件。