Zaatreh Megdad M, Bates Elizabeth R, Hooper Stephen R, Palmer Glen, Elmenshawi Ebrahim E, Courvoisie Helen E, Greenwood Robert S
Department of Neurology, Yale University, New Haven, Connecticut 06520-8018, USA.
Pediatr Neurol. 2002 Feb;26(2):134-8. doi: 10.1016/s0887-8994(01)00379-4.
Temporal lobe arachnoid cysts are common findings during brain imaging. Debate exists regarding whether they result from temporal lobe agenesis or are a malformation of the arachnoid matter. We measured temporal lobe volumes in five children with left middle cranial fossa arachnoid cysts using morphometric analysis of magnetic resonance imaging scans. Three patients had neuropsychologic testing, and two patients had positron emission tomography scanning. All patients had significantly smaller left temporal lobes compared with the right side. On neuropsychologic testing two patients had cognitive deficits suggestive of left temporal lobe dysfunction. Temporal lobes adjacent to arachnoid cysts are smaller and less metabolically active when compared with the temporal regions on the opposite side. Patients with middle cranial fossa arachnoid cysts should undergo careful assessment of temporal lobe structure and function before any therapeutic intervention.
颞叶蛛网膜囊肿是脑部影像学检查中常见的发现。关于它们是由颞叶发育不全导致还是蛛网膜物质的畸形，目前存在争议。我们对5例患有左侧中颅窝蛛网膜囊肿的儿童进行了磁共振成像扫描的形态测量分析，以测量颞叶体积。3例患者进行了神经心理学测试，2例患者进行了正电子发射断层扫描。与右侧相比，所有患者的左侧颞叶均明显较小。在神经心理学测试中，2例患者存在提示左侧颞叶功能障碍的认知缺陷。与对侧颞叶区域相比，与蛛网膜囊肿相邻的颞叶较小且代谢活性较低。在进行任何治疗干预之前，患有中颅窝蛛网膜囊肿的患者都应接受颞叶结构和功能的仔细评估。
