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颅内蛛网膜囊肿——它们会损害心理功能吗?

Intracranial arachnoid cysts--do they impair mental functions?

作者信息

Wester Knut

机构信息

Section for Neurosurgery, Dept. of Surgical Sciences, University of Bergen, 5021, Bergen, Norway.

出版信息

J Neurol. 2008 Aug;255(8):1113-20. doi: 10.1007/s00415-008-0011-y. Epub 2008 Jul 28.

Abstract

OBJECT

Arachnoid cysts are benign, congenital malformations of the arachnoid with a predilection for the temporal fossa. Radiologically, most arachnoid cysts appear to be expansive lesions, and functional imaging has shown that arachnoid cysts may cause a reorganization of cortical functions.

METHODS

The present article is based on a literature search for articles reporting dyscognition or psychiatric symptoms in arachnoid cyst patients. Emphasis is placed on systematic, prospective studies reporting results from larger series of patients. A total of five articles were identified that had investigated cognition in larger series of patients. A variety of cognitive functions were found to be impaired, including verbal perception and memory, more complex verbal tasks, visuospatial functions, and visual attention. In addition, numerous case reports were identified that link arachnoid cysts to a wide variety of neuropsychiatric and cognitive symptoms.

CONCLUSIONS

This survey indicates that arachnoid cysts may affect cognition and also that they do so in a reversible manner, as the patients' cognitive impairment seems to improve after surgical decompression of the cyst.

摘要

目的

蛛网膜囊肿是蛛网膜的良性先天性畸形,好发于颞窝。在放射学上,大多数蛛网膜囊肿表现为扩张性病变,功能成像显示蛛网膜囊肿可能导致皮质功能重组。

方法

本文基于对报道蛛网膜囊肿患者认知障碍或精神症状的文章的文献检索。重点是系统的前瞻性研究,报告来自大量患者系列的结果。共确定了五篇对大量患者进行认知研究的文章。发现多种认知功能受损,包括言语感知和记忆、更复杂的言语任务、视觉空间功能和视觉注意力。此外,还发现了大量病例报告,将蛛网膜囊肿与多种神经精神和认知症状联系起来。

结论

这项调查表明蛛网膜囊肿可能影响认知,而且这种影响是可逆的,因为囊肿手术减压后患者的认知障碍似乎有所改善。

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