在社区获得性耐甲氧西林金黄色葡萄球菌菌株中鉴定出新型葡萄球菌盒式染色体mec。
Novel type of staphylococcal cassette chromosome mec identified in community-acquired methicillin-resistant Staphylococcus aureus strains.
作者信息
Ma Xiao Xue, Ito Teruyo, Tiensasitorn Chuntima, Jamklang Mantana, Chongtrakool Piriyaporn, Boyle-Vavra Susan, Daum Robert S, Hiramatsu Keiichi
机构信息
Department of Bacteriology, Juntendo University, Tokyo, Japan.
出版信息
Antimicrob Agents Chemother. 2002 Apr;46(4):1147-52. doi: 10.1128/AAC.46.4.1147-1152.2002.
We identified a new type of staphylococcal cassette chromosome mec (SCCmec) from two community-acquired methicillin-resistant Staphylococcus aureus (MRSA) strains. The novel element, designated type IV SCCmec, had a unique combination of the class B mec gene complex and the type 2 ccr gene complex and was much smaller in size (21 to 24 kb) than previously identified SCCmec elements of hospital-acquired MRSA. Consistent with the strains' susceptibilities to various non-beta-lactam antibiotics, the type IV SCCmec was devoid of any antibiotic resistance genes other than the mecA gene.
我们从两株社区获得性耐甲氧西林金黄色葡萄球菌（MRSA）菌株中鉴定出一种新型葡萄球菌盒式染色体mec（SCCmec）。这种新型元件被命名为IV型SCCmec，它具有B类mec基因复合体和2型ccr基因复合体的独特组合，并且其大小（21至24 kb）比先前鉴定的医院获得性MRSA的SCCmec元件小得多。与这些菌株对各种非β-内酰胺类抗生素的敏感性一致，IV型SCCmec除mecA基因外没有任何抗生素抗性基因。
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