Ma Xiao Xue, Ito Teruyo, Tiensasitorn Chuntima, Jamklang Mantana, Chongtrakool Piriyaporn, Boyle-Vavra Susan, Daum Robert S, Hiramatsu Keiichi
Department of Bacteriology, Juntendo University, Tokyo, Japan.
Antimicrob Agents Chemother. 2002 Apr;46(4):1147-52. doi: 10.1128/AAC.46.4.1147-1152.2002.
We identified a new type of staphylococcal cassette chromosome mec (SCCmec) from two community-acquired methicillin-resistant Staphylococcus aureus (MRSA) strains. The novel element, designated type IV SCCmec, had a unique combination of the class B mec gene complex and the type 2 ccr gene complex and was much smaller in size (21 to 24 kb) than previously identified SCCmec elements of hospital-acquired MRSA. Consistent with the strains' susceptibilities to various non-beta-lactam antibiotics, the type IV SCCmec was devoid of any antibiotic resistance genes other than the mecA gene.
我们从两株社区获得性耐甲氧西林金黄色葡萄球菌（MRSA）菌株中鉴定出一种新型葡萄球菌盒式染色体mec（SCCmec）。这种新型元件被命名为IV型SCCmec，它具有B类mec基因复合体和2型ccr基因复合体的独特组合，并且其大小（21至24 kb）比先前鉴定的医院获得性MRSA的SCCmec元件小得多。与这些菌株对各种非β-内酰胺类抗生素的敏感性一致，IV型SCCmec除mecA基因外没有任何抗生素抗性基因。
