Asero R
Ospedale Caduti Bollatesi, Bollate, MI, Italy.
Curr Allergy Rep. 2001 Jan;1(1):18-22. doi: 10.1007/s11882-001-0092-5.
Multiple drug allergy syndrome is a clinical condition characterized by a propensity to react against different, chemically unrelated antibiotic or nonantibiotic drugs. The origin of this syndrome is still elusive. This article critically examines the medical literature on multiple drug allergy syndrome, compares and discusses recent personal observations obtained in patients with intolerance to multiple antibiotic or anti-inflammatory drugs, suggests possible pathogenic mechanisms for this type of drug allergy, and reports on current personal research in this field.
多种药物过敏综合征是一种临床病症，其特征为倾向于对不同的、化学结构不相关的抗生素或非抗生素药物产生反应。该综合征的病因仍不明确。本文对有关多种药物过敏综合征的医学文献进行了批判性审视，比较并讨论了近期在对多种抗生素或抗炎药物不耐受的患者中获得的个人观察结果，提出了这类药物过敏可能的致病机制，并报告了该领域目前的个人研究情况。
