Lydon S B, Dodds W J, Hogan W J, Arndorfer R C
Am J Dig Dis. 1975 Oct;20(10):968-70. doi: 10.1007/BF01070885.
Recent studies indicate that lower esophageal sphincter pressure is influenced by manometric assembly diameter. This study determines the effect of assembly diameter on both esophageal sphincter pressure and peristaltic pressure in the esophageal body. We performed esophageal manometric studies in 6 normal subjects using graded assembly diameters. High-fidelity recording was achieved by using a noncompliant catheter-infusion system. The results indicate that increases in assembly diameter cause significant increases in peristaltic pressure amplitudes and in resting sphincter pressure in both the smooth and striated muscle portions of the esophagus. This phenomenon is best explained by the length-tension characteristics of esophageal muscle, increased stretch causing greater contraction force.
近期研究表明，食管下括约肌压力受测压装置直径的影响。本研究旨在确定装置直径对食管括约肌压力和食管体蠕动压力的影响。我们使用不同直径的装置，对6名正常受试者进行了食管测压研究。通过使用非顺应性导管灌注系统实现了高保真记录。结果表明，装置直径的增加会导致食管平滑肌和横纹肌部分的蠕动压力幅度和静息括约肌压力显著增加。这种现象最好用食管肌肉的长度-张力特性来解释，即拉伸增加会导致更大的收缩力。
