Bandai Hideki, Tsunoda Akira, Mitsuoka Hideyuki, Arai Hajime, Sato Kiyoshi, Makita Junichi
Department of Neurosurgery, Juntendo University School of Medicine, Tokyo.
Neurol Med Chir (Tokyo). 2002 Jan;42(1):5-10. doi: 10.2176/nmc.42.5.
The fast inversion recovery (IR) technique was evaluated for the localization of gliomas. Fast IR imaging with real reconstruction and T1-weighted spin echo (SE) imaging before and after contrast administration were performed in 20 patients with gliomas. The tumor-to-white matter contrast ratio (TWCR), tumor-to-gray matter contrast ratio (TGCR), tumor-to-white matter contrast-to-noise ratio (TWCNR), and tumor-to-gray matter contrast-to-noise ratio (TGCNR) were calculated and compared. Fast IR imaging visualized tumors with significantly higher TWCR, TGCR, TWCNR, and TGCNR values (p < 0.01) than those for T1-weighted SE imaging. In particular, fast IR imaging clearly revealed seven non-enhanced tumors that were poorly visualized on T1-weighted SE imaging. Fast IR imaging showed a similar TGCR and significantly higher TWCR (p < 0.01) compared to T1-weighted SE imaging with contrast medium in 13 enhanced tumors. However, fast IR imaging showed similar TWCNR and lower TGCNR compared to T1-weighted SE imaging with contrast medium. The fast IR technique can discriminate tumors from normal cerebral tissues with high contrast and without the use of contrast medium. This technique is extremely useful for the localization of non-enhanced tumors.
对快速反转恢复（IR）技术进行了胶质瘤定位评估。对20例胶质瘤患者进行了采用实时重建的快速IR成像以及对比剂注射前后的T1加权自旋回波（SE）成像。计算并比较了肿瘤与白质对比率（TWCR）、肿瘤与灰质对比率（TGCR）、肿瘤与白质对比噪声比（TWCNR）以及肿瘤与灰质对比噪声比（TGCNR）。快速IR成像显示肿瘤的TWCR、TGCR、TWCNR和TGCNR值显著高于T1加权SE成像（p<0.01）。特别是，快速IR成像清晰显示了7个在T1加权SE成像上显示不佳的未强化肿瘤。与13个强化肿瘤的T1加权SE成像加对比剂相比，快速IR成像显示出相似的TGCR且TWCR显著更高（p<0.01）。然而，与T1加权SE成像加对比剂相比，快速IR成像显示出相似的TWCNR且TGCNR更低。快速IR技术能够在不使用对比剂的情况下以高对比度区分肿瘤与正常脑组织。该技术对未强化肿瘤的定位极为有用。
