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黄瓜花叶病毒基因组中与适应六出花相关的分子间和分子内重组。

Inter- and intramolecular recombinations in the cucumber mosaic virus genome related to adaptation to alstroemeria.

作者信息

Chen Yuh-Kun, Goldbach Rob, Prins Marcel

机构信息

Laboratory of Virology, Wageningen University, Wageningen, The Netherlands.

出版信息

J Virol. 2002 Apr;76(8):4119-24. doi: 10.1128/jvi.76.8.4119-4124.2002.

DOI:10.1128/jvi.76.8.4119-4124.2002
PMID:11907253
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC136112/
Abstract

In four distinct alstroemeria-infecting cucumber mosaic virus (CMV) isolates, additional sequences of various lengths were present in the 3' nontranslated regions of their RNAs 2 and 3, apparently the result of intra- and intermolecular recombination events. Competition experiments revealed that these recombined RNA 2 and 3 segments increased the biological fitness of CMV in alstroemeria.

摘要

在四种不同的感染六出花的黄瓜花叶病毒（CMV）分离株中，其RNA 2和RNA 3的3'非翻译区存在各种长度的额外序列，这显然是分子内和分子间重组事件的结果。竞争实验表明，这些重组的RNA 2和RNA 3片段提高了CMV在六出花中的生物学适应性。

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本文引用的文献

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RNA-RNA recombination in plant virus replication and evolution.植物病毒复制和进化中的 RNA-RNA 重组。
Annu Rev Phytopathol. 2011;49:415-43. doi: 10.1146/annurev-phyto-072910-095351.
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FUNCTIONS OF THE 3'-UNTRANSLATED REGIONS OF POSITIVE STRAND RNA VIRAL GENOMES.正链RNA病毒基因组3'非翻译区的功能
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Arch Virol. 2001 Aug;146(8):1631-6. doi: 10.1007/s007050170085.
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Factors regulating template switch in vitro by viral RNA-dependent RNA polymerases: implications for RNA-RNA recombination.病毒RNA依赖性RNA聚合酶在体外调节模板转换的因素：对RNA-RNA重组的影响
Proc Natl Acad Sci U S A. 2001 Apr 24;98(9):4972-7. doi: 10.1073/pnas.081077198. Epub 2001 Apr 17.
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A subpopulation of RNA 1 of Cucumber mosaic virus contains 3' termini originating from RNAs 2 or 3.
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