Department of Plant Pathology and Environmental Biology, and The Huck Institutes of The Life Sciences, Center for Infectious Disease Dynamics, Pennsylvania State University, University Park, PA, USA.
J Virol. 2013 Jan;87(2):1264-9. doi: 10.1128/JVI.01892-12. Epub 2012 Oct 31.
Interstrain recombinants were observed in the progenies of the Cucumber mosaic virus (CMV) reassortant L(1)L(2)F(3) containing RNAs 1 and 2 from LS-CMV and RNA 3 from Fny-CMV. We characterized these recombinants, and we found that their fixation was controlled by the nature of the replicating RNAs 1 and 2. We demonstrate that the 2b gene partially affects this fixation process, but only in the context of homologous RNAs 1 and 2.
在含有 LS-CMV 的 RNA1 和 RNA2 以及 Fny-CMV 的 RNA3 的黄瓜花叶病毒(CMV)重组体 L(1)L(2)F(3)的后代中观察到了菌株间重组体。我们对这些重组体进行了特征分析,发现它们的固定受复制 RNA1 和 RNA2 的性质控制。我们证明 2b 基因部分影响该固定过程,但仅在同源 RNA1 和 RNA2 的情况下。