Cooney D R, Crosfeld J L
Ann Surg. 1975 Nov;182(5):590-6. doi: 10.1097/00000658-197511000-00010.
This report combines the findings and treatment in 15 infants and children with pancreatic pseudocysts with 60 additional cases from a literature review. The mean age at diagnosis was 7.5 years with pseudocyst being more common in boys (44:31). Sixty per cent were due to trauma, while in 32% the cause was unknown. Abdominal pain (68%), a mass (64%), and vomiting (52%) were the most frequent findings. The serum amylase was elevated and the upper gastrointestinal contrast study consistent with a mass in 88% of cases. Operative treatment included external drainage in 25 children (33%), cystgastrostomy or cyst-jejunostomy in 34 (45%), excision in 10 (13%) and miscellaneous procedures in 6 (8%). Complications were relatively few and there were no deaths recorded. Recurrence rate for cyst-gastrostomy was 4.7%, cyst-jejunostomy 7.6%, external drainage 8% and cyst-duodenostomy 50%. External drainage operations had prolonged cutaneous drainage. These observations suggest the appropriate operation is determined by the location and duration of pseudocyst. Internal drainage is preferred and avoids complications seen following resection and external drainage. Cyst-gastrostomy is effective when the pseudocyst is retrogastric and adherent to the stomach wall. Cyst-jejunostomy is most useful in instances in which the pseudocyst in not adherent to the stomach wall. Low recurrence rates and a zero mortality rate makes operative treatment highly acceptable therapy. Low recurrence rates are expected in childhood cases, (particularly related to trauma) due to an absence of underlying pancreatic disease and ductal obstruction.
本报告汇总了15例婴幼儿及儿童胰腺假性囊肿的诊疗结果,并结合文献回顾的另外60例病例。诊断时的平均年龄为7.5岁,假性囊肿在男孩中更为常见(44例:31例)。60%的病例由创伤引起,32%病因不明。最常见的表现为腹痛(68%)、肿块(64%)和呕吐(52%)。血清淀粉酶升高,上消化道造影检查显示88%的病例有肿块。手术治疗包括25例儿童(33%)行外引流,34例(45%)行囊肿胃吻合术或囊肿空肠吻合术,10例(13%)行切除术,6例(8%)行其他手术。并发症相对较少,无死亡记录。囊肿胃吻合术的复发率为4.7%,囊肿空肠吻合术为7.6%,外引流为8%,囊肿十二指肠吻合术为50%。外引流手术的皮肤引流时间延长。这些观察结果表明,合适的手术方式取决于假性囊肿的位置和持续时间。首选内引流,可避免切除和外引流后出现的并发症。当假性囊肿位于胃后方并与胃壁粘连时,囊肿胃吻合术有效。囊肿空肠吻合术在假性囊肿未与胃壁粘连的情况下最为有用。低复发率和零死亡率使手术治疗成为高度可接受的治疗方法。由于儿童病例(特别是与创伤相关的病例)不存在潜在的胰腺疾病和导管阻塞,预计复发率较低。