发育生物学：没有RECK，血管生成则遭到破坏。
Developmental biology: vasculogenesis is a wreck without RECK.
作者信息
Welm Bryan, Mott Joni, Werb Zena
机构信息
Department of Anatomy, University of California, San Francisco, CA 94143-0452, USA.
出版信息
Curr Biol. 2002 Mar 19;12(6):R209-11. doi: 10.1016/s0960-9822(02)00752-2.
Abstract
The unique membrane-associated inhibitor of matrix metalloproteinases, RECK, is required for vascular maturation during embryogenesis. The phenotype of a loss of function mutation of RECK shows the importance of pericellular proteolysis in development.
摘要
基质金属蛋白酶的独特膜相关抑制剂RECK是胚胎发育过程中血管成熟所必需的。RECK功能丧失突变的表型显示了细胞周围蛋白水解在发育中的重要性。
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