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多形毕赤酵母细胞和原生质体合成β-葡聚糖酶及其他细胞外蛋白:2-脱氧-D-葡萄糖的作用

Synthesis of beta-glucanase and other extracellular proteins by cells and protoplasts of the yeast Pichia polymorpha: effect of 2-deoxy-D-glucose.

作者信息

Villa T G, Notario V, Villanueva J R

出版信息

Arch Microbiol. 1975 Nov 7;105(3):335-7. doi: 10.1007/BF00447154.

DOI:10.1007/BF00447154
PMID:1190960
Abstract

The synthesis of beta-glucanase either by cells or by protoplasts of the yeast Pichia polymorpha has been found to occur in the presence of 2-deoxy-D-glucose in the growth medium. On the other hand, the synthesis of typical extracellular proteins such as invertase and acid phosphatase is strongly affected by the presence of the drug. The degree of inhibition is, however, directly related to the 2-deoxy-D-glucose concentration.

摘要

已发现多形毕赤酵母的细胞或原生质体在生长培养基中存在2-脱氧-D-葡萄糖的情况下会合成β-葡聚糖酶。另一方面,典型的细胞外蛋白如转化酶和酸性磷酸酶的合成受到该药物存在的强烈影响。然而,抑制程度与2-脱氧-D-葡萄糖浓度直接相关。

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Synthesis of beta-glucanase and other extracellular proteins by cells and protoplasts of the yeast Pichia polymorpha: effect of 2-deoxy-D-glucose.多形毕赤酵母细胞和原生质体合成β-葡聚糖酶及其他细胞外蛋白:2-脱氧-D-葡萄糖的作用
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引用本文的文献

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Biochem J. 1976 Dec 1;159(3):555-62. doi: 10.1042/bj1590555.
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On the effect of glucono-delta-lactone on the yeast Pichia polymorpha.关于葡萄糖酸-δ-内酯对多形毕赤酵母的影响
Arch Microbiol. 1976 Aug;109(1-2):157-61. doi: 10.1007/BF00425129.

本文引用的文献

1
METABOLIC STUDIES WITH 2-DEOXYHEXOSES. I. MECHANISMS OF INHIBITION OF GROWTH AND FERMENTATION IN BAKER'S YEAST.2-脱氧己糖的代谢研究。I. 对面包酵母生长和发酵的抑制机制。
Biochim Biophys Acta. 1964 May 11;86:216-23. doi: 10.1016/0304-4165(64)90045-5.
2
Use of glucose oxidase, peroxidase, and O-dianisidine in determination of blood and urinary glucose.葡萄糖氧化酶、过氧化物酶和邻联茴香胺在血液及尿液葡萄糖测定中的应用
Lancet. 1957 Aug 24;273(6991):368-70. doi: 10.1016/s0140-6736(57)92595-3.
3
Inhibitory effect of 2-deoxy-d-glucose on the formation of the cell wall in yeast protoplasts.
2-脱氧-D-葡萄糖对酵母原生质体细胞壁形成的抑制作用。
J Bacteriol. 1969 May;98(2):744-8. doi: 10.1128/jb.98.2.744-748.1969.
4
Lysis of yeast cell walls induced by 2-deoxyglucose at their sites of glucan synthesis.2-脱氧葡萄糖在葡聚糖合成位点诱导酵母细胞壁溶解。
J Bacteriol. 1968 Mar;95(3):1169-72. doi: 10.1128/jb.95.3.1169-1172.1968.
5
Beta-glucanases of the yeast Pichia polymorpha.多形毕赤酵母的β-葡聚糖酶
Arch Microbiol. 1975 Jun 22;104(2):201-6. doi: 10.1007/BF00447325.