Heedman P A, Strang P
Palliative Advisory Team, Linköping University Hospital, Sweden.
Anticancer Res. 2001 Nov-Dec;21(6A):4077-82.
Four hundred and thirty-one cancer patients were assessed with the ESAS and a VAS-QoL at admission to Hospital-based home care (HBHC) and subsequently.
Pain and nausea were well-controlled (mean 2.5 and 1.8) whereas patients were less satisfied with appetite, activity and sense of well-being. Dyspnoea and anxiety (lung cancer, p<0.001 and p<0.01) and pain (prostate cancer, p<0.01), were related to diagnosis while activity, drowsiness, appetite and well-being to survival (p<0.05 to p<0.001). The correlations between individual symptoms and well-being were low (0.2-0.5), whereas the correlation between well-being and the Symptom Distress Score (SDS) was 0.76. "Well-being" was a better word to use than QoL.
ESAS is useful in HBHC and data show that symptoms other than merely pain and nausea are of importance. As the global measurement (one VAS) of well-being has a high correlation with SDS, this single measurement may be clinically adequate for quality assurance of symptom control in dying cancer patients.
431名癌症患者在入院接受医院居家护理（HBHC）时及之后接受了埃德蒙顿症状评估量表（ESAS）和视觉模拟量表-生活质量（VAS-QoL）评估。
疼痛和恶心得到良好控制（平均分为2.5和1.8），而患者对食欲、活动和幸福感的满意度较低。呼吸困难和焦虑（肺癌，p<0.001和p<0.01）以及疼痛（前列腺癌，p<0.01）与诊断有关，而活动、嗜睡、食欲和幸福感与生存有关（p<0.05至p<0.001）。个体症状与幸福感之间的相关性较低（0.2 - 0.5），而幸福感与症状困扰评分（SDS）之间的相关性为0.76。使用“幸福感”一词比使用“生活质量”更好。
ESAS在HBHC中很有用，数据表明除了疼痛和恶心之外的其他症状也很重要。由于幸福感的整体测量（一个VAS）与SDS具有高度相关性，这种单一测量在临床上可能足以用于临终癌症患者症状控制的质量保证。
