Department of Radiation Oncology and Competence Center for Palliative Care, University Hospital Zurich and University of Zurich, Zurich, Switzerland.
Department of Radiation Oncology and Competence Center for Palliative Care, University Hospital Zurich and University of Zurich, Zurich, Switzerland; Department of Consultation-Liaison Psychiatry and Psychosomatic Medicine, University Hospital Zurich and University of Zurich, Zurich, Switzerland.
ESMO Open. 2020 Nov;5(Suppl 4):e000837. doi: 10.1136/esmoopen-2020-000837.
Patient-reported outcomes (PROs) are important tools in patient-centred medicine and allow for individual assessment of symptom burden and aspects of patients' quality of life. While sex and gender differences have emerged in preclinical and clinical medicine, these differences are not adequately represented in the development and use of patient-reported outcome measures. However, even in personalised approaches, undesirable biases may occur when samples are unbalanced for certain characteristics, such as sex or gender. This review summarises the current status of the literature and trends in PROs with a focus on sex and gender aspects.
患者报告的结局（PROs）是患者为中心医学的重要工具，可用于个体评估症状负担和患者生活质量的各个方面。尽管在临床前和临床医学中已经出现了性别差异，但在患者报告结局测量的开发和使用中，这些差异并没有得到充分体现。然而，即使在个性化方法中，当样本在某些特征（如性别）上不平衡时，也可能会出现不理想的偏差。本综述总结了目前文献的现状和 PROs 的趋势，重点关注性别方面。
