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人足月胎盘催乳素在胎盘内的分布。

The distribution of placental lactogen in the human term placenta.

作者信息

Gau G, Chard T

出版信息

Br J Obstet Gynaecol. 1975 Oct;82(10):790-3. doi: 10.1111/j.1471-0528.1975.tb00575.x.

DOI:10.1111/j.1471-0528.1975.tb00575.x
PMID:1191587
Abstract

Serial frozen sections of human term placentae were examined by quantitative morphology and, after extraction, by a radioimmunoassay for human placental lactogen (HPL). The total quantity of HPL in the placenta was estimated as 720 mg. The amount of HPL was related to the amount of trophoblast in any area, but otherwise did not vary in different parts of the placenta. A semi-logarithmic relationship was observed between the amount of HPL and the percentage trophoblast in a section. It is suggested that the amount of HPL in a given area of the placenta is related to the blood-flow in that area.

摘要

通过定量形态学方法对足月人类胎盘的连续冰冻切片进行检查,并在提取后通过放射免疫分析法检测人胎盘催乳素(HPL)。胎盘内HPL的总量估计为720毫克。HPL的含量与任何区域的滋养层数量有关,但在胎盘的不同部位并无其他差异。在切片中观察到HPL含量与滋养层百分比之间呈半对数关系。有人认为,胎盘特定区域内HPL的含量与该区域的血流量有关。

相似文献

1
The distribution of placental lactogen in the human term placenta.人足月胎盘催乳素在胎盘内的分布。
Br J Obstet Gynaecol. 1975 Oct;82(10):790-3. doi: 10.1111/j.1471-0528.1975.tb00575.x.
2
The immunocytochemical demonstration of human placental lactogenic hormone (hPL): a parameter for the functional capacity of the trophoblast.人胎盘催乳素(hPL)的免疫细胞化学检测:滋养层细胞功能能力的一个指标。
Placenta. 1983;4 Spec No:541-8.
3
Purified first and third trimester placental trophoblasts differ in in vitro hormone secretion.纯化的孕早期和孕晚期胎盘滋养层细胞在体外激素分泌方面存在差异。
J Clin Endocrinol Metab. 1990 Apr;70(4):1187-92. doi: 10.1210/jcem-70-4-1187.
4
Preliminary report: immunoperoxidase-linked human placental lactogen as a histopathologic index of perinatal morbidity and mortality.初步报告:免疫过氧化物酶连接的人胎盘催乳素作为围产期发病率和死亡率的组织病理学指标
Pediatr Pathol. 1983 Oct-Dec;1(4):469-74. doi: 10.3109/15513818309025879.
5
Identification of "big" human placental lactogen in placenta and serum.
Endocrinology. 1975 Dec;97(6):1364-72. doi: 10.1210/endo-97-6-1364.
6
The synthesis and secretion of human placental lactogen (hPL) in cultured term placenta.足月胎盘培养物中人胎盘催乳素(hPL)的合成与分泌
Mol Cell Endocrinol. 1982 Apr;26(1-2):189-99. doi: 10.1016/0303-7207(82)90016-8.
7
Serial human placental lactogen estimations in serum and placental weight-for-dates.
Br J Obstet Gynaecol. 1975 Nov;82(11):899-902. doi: 10.1111/j.1471-0528.1975.tb00595.x.
8
[Immunocytochemical localization of human chorionic gonadotropin and placental lactogen in normal placentae].[人绒毛膜促性腺激素和胎盘催乳素在正常胎盘中的免疫细胞化学定位]
Zhonghua Fu Chan Ke Za Zhi. 1991 May;26(3):155-7, 188.
9
[Immunohistochemical studies of the HPL concentration in the mature human placenta].[成熟人胎盘绒毛膜促乳素浓度的免疫组织化学研究]
Z Geburtshilfe Perinatol. 1984 May-Jun;188(3):115-8.
10
Characterization of placental lactogen release from perifused human trophoblast cells.
Placenta. 1988 Mar-Apr;9(2):129-38. doi: 10.1016/0143-4004(88)90011-2.

引用本文的文献

1
Immunolocalization of alpha and beta chains of human chorionic gonadotropin, placental lactogen and pregnancy-specific beta-glycoprotein in term placenta by a touch preparation method.采用触片制备方法对足月胎盘中人绒毛膜促性腺激素α和β链、胎盘催乳素及妊娠特异性β-糖蛋白进行免疫定位。
Histochemistry. 1987;88(1):57-60. doi: 10.1007/BF00490168.
2
The prognostic value of human placental lactogen levels in threatened abortion in general practice.人胎盘生乳素水平在全科医疗中对先兆流产的预后价值。
J R Coll Gen Pract. 1977 Feb;27(175):91-2.