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化疗与放疗。何时该停止。

Chemotherapy and radiotherapy. When to call it quits.

作者信息

Mitchell Geoff, Currow David

机构信息

University of Queensland Centre for General Practice, Centre for Palliative Care Education and Research, Queensland, Australia.

出版信息

Aust Fam Physician. 2002 Feb;31(2):129-33.

PMID:11917822
Abstract

BACKGROUND

Patients diagnosed with cancer are often treated with chemotherapy and radiotherapy with curative intent. The transition from curative to palliative intent involves re-evaluation of treatment, and has to take into account the attitudes, beliefs and life aims of the patient.

OBJECTIVE

To discuss the difficulties in determining when to cease chemotherapy and radiotherapy in patients with advanced cancer.

DISCUSSION

The concept of treatment evaluation using a 'burden versus benefit' paradigm is discussed. Treatment aims must be in concordance with those of the patient, which are often couched in functional terms or linked to future significant life events. Chemotherapy and radiotherapy can offer patients in the palliative phase of cancer illness, benefits in terms of relief of symptoms and meaningful prolongation of life, and should be considered in appropriate circumstances.

摘要

背景

被诊断患有癌症的患者通常接受旨在治愈的化疗和放疗。从治愈性意图到姑息性意图的转变涉及重新评估治疗,并且必须考虑患者的态度、信念和生活目标。

目的

探讨确定晚期癌症患者何时停止化疗和放疗的困难。

讨论

讨论了使用“负担与益处”范式进行治疗评估的概念。治疗目标必须与患者的目标一致,患者的目标通常用功能术语表述或与未来重大生活事件相关。化疗和放疗可为处于癌症姑息治疗阶段的患者带来缓解症状和有意义地延长生命方面的益处,在适当情况下应予以考虑。

相似文献

1
Chemotherapy and radiotherapy. When to call it quits.化疗与放疗。何时该停止。
Aust Fam Physician. 2002 Feb;31(2):129-33.
2
Palliative chemotherapy preferences and factors that influence patient choice in incurable advanced cancer.姑息性化疗的偏好以及影响晚期不治之症患者选择的因素。
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[Treatment of cancer: surgery, radiotherapy, chemotherapy, hormonal therapy. Multidisciplinary therapeutic decision making and informing the patient].[癌症治疗:手术、放疗、化疗、激素治疗。多学科治疗决策及告知患者]
Rev Prat. 2007 Feb 28;57(4):429-40; quiz 440.
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Curative and palliative aspects of regional chemotherapy in combination with surgery.区域化疗联合手术的治疗与姑息治疗方面
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Simultaneous care: a model approach to the perceived conflict between investigational therapy and palliative care.同步护理:一种应对试验性治疗与姑息治疗之间感知冲突的模式方法。
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Palliative chemotherapy: no longer a contradiction in terms.姑息性化疗:不再是自相矛盾的说法。
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Measuring the benefit and toxicity of palliative radiotherapy.衡量姑息性放疗的益处和毒性。
Can J Oncol. 1996 Feb;6 Suppl 1:86-9.
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[Key ethic discussions in hospice/palliative care].[临终关怀/姑息治疗中的关键伦理讨论]
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Advanced breast cancer patients' perceptions of decision making for palliative chemotherapy.晚期乳腺癌患者对姑息性化疗决策的看法。
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[Management of emesis in cancer patients].[癌症患者呕吐的管理]
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引用本文的文献

1
Palliative chemotherapy beyond three courses conveys no survival or consistent quality-of-life benefits in advanced non-small-cell lung cancer.对于晚期非小细胞肺癌,超过三个疗程的姑息性化疗并不能带来生存获益或持续的生活质量改善。
Br J Cancer. 2006 Oct 23;95(8):966-73. doi: 10.1038/sj.bjc.6603383. Epub 2006 Oct 3.
2
Improving the quality of palliative care for ambulatory patients with lung cancer.提高肺癌门诊患者的姑息治疗质量。
BMJ. 2005 Jun 4;330(7503):1309-13. doi: 10.1136/bmj.330.7503.1309.