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在隐孢子虫病水源性暴发期间增加粪便采样,并不能提高对其他粪便病原体的检测率。

Increased stool sampling during a waterborne outbreak of cryptosporidiosis does not increase the detection of other faecal pathogens.

作者信息

Qamruddin A O, Keaney M G L, McCann R, Chadwick P R

机构信息

Department of Medical Microbiology, Salford Royal Hospitals NHS Trust, Hope Hospital, Salford M6 8HD, UK.

出版信息

J Clin Pathol. 2002 Apr;55(4):271-4. doi: 10.1136/jcp.55.4.271.

DOI:10.1136/jcp.55.4.271
PMID:11919210
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1769633/
Abstract

AIMS

To ascertain the effect of enhanced surveillance following an outbreak of waterborne cryptosporidiosis on the number of faecal specimens submitted to the local microbiology laboratory and the number positive for common enteric pathogens. The outbreak provided an opportunity to estimate the extent of routine under ascertainment of common enteric pathogens.

METHOD

Retrospective search of the computerised microbiology system database for details of faecal examination requests for the period 26 April to 6 June in 1998 and 1999 (period of outbreak).

RESULTS

Specimens were received from 378 community patients during the six week period 26 April to 6 June 1999. This was double that for the same period in 1998 (a non-outbreak year). Oocysts of Cryptosporidium parvum were detected in 59 patients, an eightfold increase compared with the same period in 1998. Despite the greater number of patients tested, the detection of other pathogens in patients with gastroenteritis was not altered when compared with the same period in the previous year.

CONCLUSION

This study found no evidence of under ascertainment of gastrointestinal infection (common bacterial pathogens and rotavirus) by local general practitioners.

摘要

目的

确定水源性隐孢子虫病暴发后加强监测对提交至当地微生物实验室的粪便标本数量以及常见肠道病原体阳性标本数量的影响。此次暴发为估计常见肠道病原体常规漏检程度提供了契机。

方法

对计算机化微生物系统数据库进行回顾性检索,以获取1998年和1999年4月26日至6月6日(暴发期)粪便检查申请的详细信息。

结果

在1999年4月26日至6月6日的六周期间,共收到378名社区患者的标本。这是1998年(非暴发年)同期的两倍。在59名患者中检测到微小隐孢子虫卵囊,与1998年同期相比增加了八倍。尽管检测的患者数量更多,但与上一年同期相比,胃肠炎患者中其他病原体的检测情况并未改变。

结论

本研究未发现当地全科医生漏检胃肠道感染(常见细菌病原体和轮状病毒)的证据。

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Increased stool sampling during a waterborne outbreak of cryptosporidiosis does not increase the detection of other faecal pathogens.在隐孢子虫病水源性暴发期间增加粪便采样,并不能提高对其他粪便病原体的检测率。
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本文引用的文献

1
A study of infectious intestinal disease in England: microbiological findings in cases and controls.英国传染性肠道疾病研究:病例与对照的微生物学发现
Commun Dis Public Health. 1999 Jun;2(2):108-13.
2
Outbreak of cryptosporidiosis in north west England.
Commun Dis Rep CDR Wkly. 1999 May 14;9(20):175, 178.
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Study of infectious intestinal disease in England: rates in the community, presenting to general practice, and reported to national surveillance. The Infectious Intestinal Disease Study Executive.英国感染性肠道疾病研究:社区发病率、全科医疗就诊情况及国家监测报告。感染性肠道疾病研究执行组。
BMJ. 1999 Apr 17;318(7190):1046-50. doi: 10.1136/bmj.318.7190.1046.
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Epidemiologic aspects of human cryptosporidiosis and the role of waterborne transmission.人类隐孢子虫病的流行病学特征及经水传播的作用。
Epidemiol Rev. 1996;18(2):118-36. doi: 10.1093/oxfordjournals.epirev.a017920.