Majowicz Shannon E, Edge Victoria L, Fazil Aamir, McNab W Bruce, Doré Kathryn A, Sockett Paul N, Flint James A, Middleton Dean, McEwen Scott A, Wilson Jeffery B
Department of Population Medicine, University of Guelph, Guelph, ON, Canada.
Can J Public Health. 2005 May-Jun;96(3):178-81. doi: 10.1007/BF03403685.
In Ontario, infectious gastrointestinal illness (IGI) reporting can be represented by a linear model of several sequential steps required for a case to be captured in the provincial reportable disease surveillance system. Since reportable enteric data are known to represent only a small fraction of the total IGI in the community, the objective of this study was to estimate the under-reporting rate for IGI in Ontario.
A distribution of plausible values for the under-reporting rate was estimated by specifying input distributions for the proportions reported at each step in the reporting chain, and multiplying these distributions together using simulation methods. Input distributions (type of distribution and parameters) for the proportion of cases reported at each step of the reporting chain were determined using data from the Public Health Agency of Canada's National Studies on Acute Gastrointestinal Illness (NSAGI) initiative.
For each case of enteric illness reported to the province of Ontario, the estimated number of cases of IGI in the community ranged from 105 to 1,389, with a median of 285, and a mean and standard deviation of 313 and 128, respectively.
Each case of enteric illness reported to the province of Ontario represents an estimated several hundred cases of IGI in the community. Thus, reportable disease data should be used with caution when estimating the burden of such illness. Program planners and public health personnel may want to consider this fact when developing population-based interventions.
在安大略省,感染性胃肠道疾病(IGI)报告可由省级法定传染病监测系统中捕获病例所需的几个连续步骤的线性模型表示。由于已知法定肠道疾病数据仅占社区中IGI总数的一小部分,本研究的目的是估计安大略省IGI的漏报率。
通过指定报告链中每个步骤报告比例的输入分布,并使用模拟方法将这些分布相乘,估计漏报率的合理值分布。报告链中每个步骤报告病例比例的输入分布(分布类型和参数)使用加拿大公共卫生局急性胃肠道疾病国家研究(NSAGI)倡议的数据确定。
对于向安大略省报告的每例肠道疾病病例,社区中IGI病例的估计数量在105至1389例之间,中位数为285例,均值和标准差分别为313例和128例。
向安大略省报告的每例肠道疾病病例估计代表社区中数百例IGI病例。因此,在估计此类疾病的负担时,应谨慎使用法定疾病数据。项目规划者和公共卫生人员在制定基于人群的干预措施时可能需要考虑这一事实。