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斯温顿和牛津郡爆发水源性隐孢子虫病。

An outbreak of waterborne cryptosporidiosis in Swindon and Oxfordshire.

作者信息

Richardson A J, Frankenberg R A, Buck A C, Selkon J B, Colbourne J S, Parsons J W, Mayon-White R T

机构信息

Department of Public Health Medicine, Wessex Regional Health Authority, Winchester.

出版信息

Epidemiol Infect. 1991 Dec;107(3):485-95. doi: 10.1017/s0950268800049189.

DOI:10.1017/s0950268800049189
PMID:1752298
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2272087/
Abstract

An outbreak of cryptosporidiosis resulted in 516 cases in Wiltshire and Oxfordshire. The outbreak caused widespread interest and led to an official inquiry. The majority of cases were in children; 8% of cases were admitted to hospital and the median duration of illness was 3 weeks. The geographical distribution of cases matched the distribution of water supplies from three treatment works and cryptosporidium oocysts were found at these works and in the treated water. Attack rates in electoral wards supplied by the three treatment works were significantly higher than in other wards. The cause of the outbreak appeared to be the failure of normal treatment to remove oocysts. Measures at the treatment works reduced the number of oocysts detected in treated water, after which the outbreak came to an end. The conclusion of the investigations was that cryptosporidiosis is a risk of conventionally treated public water supplies.

摘要

威尔特郡和牛津郡爆发了隐孢子虫病,导致516例病例。此次疫情引起了广泛关注,并引发了官方调查。大多数病例为儿童;8%的病例住院治疗,疾病的中位持续时间为3周。病例的地理分布与来自三个处理厂的供水分布相匹配,并且在这些处理厂和处理后的水中发现了隐孢子虫卵囊。由这三个处理厂供水的选区的发病率明显高于其他选区。疫情爆发的原因似乎是常规处理未能去除卵囊。处理厂采取的措施减少了处理后水中检测到的卵囊数量,此后疫情结束。调查结论是,隐孢子虫病是传统处理的公共供水存在的一种风险。

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本文引用的文献

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Human cryptosporidiosis in immunocompetent and immunodeficient persons. Studies of an outbreak and experimental transmission.免疫功能正常和免疫功能低下人群中的人体隐孢子虫病。一次暴发及实验性传播的研究。
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Staining of cryptosporidia by a modified Ziehl-Neelsen technique.采用改良齐-尼氏技术对隐孢子虫进行染色。
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The incidence of cryptosporidiosis: a two-year prospective survey in a children's hospital.隐孢子虫病的发病率:在一家儿童医院进行的为期两年的前瞻性调查。
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Outbreak of cryptosporidiosis in a day-care center.日托中心隐孢子虫病暴发。
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Cryptosporidiosis in hospital personnel. Evidence for person-to-person transmission.医院工作人员中的隐孢子虫病。人传人传播的证据。
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