特发性心脏传导阻滞：与白癜风、甲状腺疾病、恶性贫血和糖尿病的关联。
Idiopathic heart block: association with vitiligo, thyroid disease, pernicious anaemia, and diabetes mellitus.
作者信息
Fairfax A J, Leatham A
出版信息
Br Med J. 1975 Nov 8;4(5992):322-4. doi: 10.1136/bmj.4.5992.322.
Abstract
Out of 100 patients with chronic heart block 16 had one or more autoimmune disorders-namely, vitiligo (5,) hypothyroidism (4), Graves's disease (1), pernicious anaemia (2), and diabetes mellitus (9). All these disorders occurred with greater frequency than normal and were more prevalent than in a group of hospital inpatients of comparable age. Autoantibodies were not increased. We suggest that among patients with idiopathic heart block there is a subgroup with multiple autoimmune disorders.
摘要
在100例慢性心脏传导阻滞患者中，16例患有一种或多种自身免疫性疾病，即白癜风（5例）、甲状腺功能减退症（4例）、格雷夫斯病（1例）、恶性贫血（2例）和糖尿病（9例）。所有这些疾病的发生频率均高于正常水平，且比一组年龄相仿的住院患者更为普遍。自身抗体并未增加。我们认为，在特发性心脏传导阻滞患者中，存在一个患有多种自身免疫性疾病的亚组。
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G Ital Dermatol Minerva Dermatol. 1971 Nov;46(11):487-91.
3
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4
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Z Gesamte Inn Med. 1980 Apr 1;35(7):285-9.
5
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Acta Clin Belg. 1971;26(6):380-7. doi: 10.1080/17843286.1971.11716806.
6
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8
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Ir J Med Sci. 1974 Jan;143(1):42-53. doi: 10.1007/BF03004740.
9
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10
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Lancet. 1969 Oct 4;2(7623):721-2. doi: 10.1016/s0140-6736(69)90430-9.
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8
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9
Pathological studies in sinoatrial disorder (sick sinus syndrome).
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10
Skeletal muscle pathology in chronic heart block.
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本文引用的文献
1
Incidence of pernicious anemia; number of patient in the county of Odense, Denmark, in December 1950.
Acta Med Scand. 1952 Feb 14;141(6):433-9.
2
ETIOLOGY AND PATHOLOGY OF BILATERAL BUNDLE BRANCH BLOCK IN RELATION TO COMPLETE HEART BLOCK.
Prog Cardiovasc Dis. 1964 Mar;6:409-44. doi: 10.1016/s0033-0620(64)80001-3.
3
THE AETIOLOGY OF COMPLETE HEART-BLOCK.
Br Med J. 1963 Nov 9;2(5366):1149-53. doi: 10.1136/bmj.2.5366.1149.
4
Complete heart block with Stokes-Adams syndrome due to rheumatoid heart disease: report of a case with autopsy findings.
N Engl J Med. 1960 May 19;262:1012-4. doi: 10.1056/NEJM196005192622004.
5
Clinical and pathologic studies in the hereditary syndrome of a long QT interval, syncopal spells and sudden death.
Chest. 1970 Sep;58(3):236-43. doi: 10.1378/chest.58.3.236.
6
Vitiligo and pernicious anemia.
Arch Dermatol. 1970 Jan;101(1):82-5.
7
Pathology of the conduction system in cardiac rejection.
Circulation. 1969 May;39(5):567-75. doi: 10.1161/01.cir.39.5.567.
8
Reversible atrioventricular block in myxedema.
Chest. 1973 Apr;63(4):582-5. doi: 10.1378/chest.63.4.582.
9
The pathology of atrioventricular block.
Cardiovasc Clin. 1972;4(2):159-86.
10
Autoimmunity in a rural community.
Clin Exp Immunol. 1972 Sep;12(1):79-87.
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