Enzinger F M, Harvey D A
Cancer. 1975 Nov;36(5):1852-9. doi: 10.1002/1097-0142(197511)36:5<1852::aid-cncr2820360542>3.0.co;2-u.
Spindle cell lipoma is a specific type of lipoma that is easily mistaken for a liposarcoma. An analysis of 114 cases of this tumor from the files of the Armed Forces Institute of Pathology reveals that is occurs chiefly in male patients between 45 and 70 years of age and affects the regions of the shoulder and posterior neck almost exclusively. Microscopically, it consists of an intricate mixture of lipocytes and uniform spindle cells within a matrix of mucinous material traversed by a varying number of birefringent collagen fibers. Ultrastructural studies in one case support the fibroblastic nature of the spindle cells. Followup information obtained in 63 patients with this lesion revealed a uniformly favorable clinical course, indicating that local excision is the treatment of choice, and that there is no need or reason for radical surgical procedures.
梭形细胞脂肪瘤是一种特殊类型的脂肪瘤，很容易被误诊为脂肪肉瘤。对武装部队病理研究所档案中的114例该肿瘤病例进行分析发现，它主要发生在45至70岁的男性患者中，几乎仅累及肩部和后颈部区域。在显微镜下，它由脂肪细胞和均匀的梭形细胞在黏液样物质基质中复杂混合而成，有数量不等的双折射胶原纤维穿过。对1例患者进行的超微结构研究支持了梭形细胞的成纤维细胞性质。对63例患有这种病变的患者获得的随访信息显示临床病程一致良好，表明局部切除是首选治疗方法，而且没有必要也没有理由进行根治性手术。
