十二指肠乳头旁憩室在胆石症中的作用。
The role of juxtapapillary duodenal diverticula in biliary stone disease.
作者信息
Christoforidis Emmanouil, Goulimaris Ioannis, Kanellos Ioannis, Tsalis Konstantinos, Dadoukis Ioannis
机构信息
IV Surgical Department, Aristotelian University of Thessaloniki, Hospital "G. Papanikolaou," Thessaloniki, Greece.
出版信息
Gastrointest Endosc. 2002 Apr;55(4):543-7. doi: 10.1067/mge.2002.122615.
BACKGROUND
Duodenal diverticula are acquired lesions found more often in older patients; when located near the major duodenal papilla they are called juxtapapillary. The prevalence of juxtapapillary duodenal diverticula (JDD) in the general population is around 20%; they are often associated with biliary lithiasis. This study assessed the association between JDD and biliary stone disease, particularly choledocholithiasis.
METHODS
Four hundred fifty ERCPs were performed in 420 patients from 1995 through 1999. The results for 300 ERCPs that were performed in 285 patients for suspected biliary lithiasis were analyzed.
RESULTS
JDD were present in 21.42% of the 420 patients; most were found in patients in the eighth and ninth decades of life. Patients with JDD had bile duct stones alone more often than patients without JDD (44% vs. 24%). According to their features, these bile duct stones were characterized as mainly primary. The existence of JDD influences bile duct diameter irrespectively of the presence of bile duct stones.
CONCLUSIONS
JDD are important causative factors in the formation of bile duct stones.
背景
十二指肠憩室是后天获得性病变，多见于老年患者；位于十二指肠乳头附近时称为乳头旁憩室。普通人群中乳头旁十二指肠憩室（JDD）的患病率约为20%；它们常与胆石症相关。本研究评估了JDD与胆石病，尤其是胆总管结石之间的关联。
方法
1995年至1999年对420例患者进行了450次内镜逆行胰胆管造影（ERCP）。对285例疑似胆石症患者进行的300次ERCP结果进行了分析。
结果
420例患者中21.42%存在JDD；大多数见于80岁和90岁的患者。有JDD的患者单纯胆管结石的发生率高于无JDD的患者（44%对24%）。根据其特征，这些胆管结石主要为原发性。无论胆管结石是否存在，JDD的存在都会影响胆管直径。
结论
JDD是胆管结石形成的重要致病因素。
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