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具有抗菌活性的刺矢车菊次生代谢产物。

Secondary metabolites from Centaurea deusta with antimicrobial activity.

作者信息

Karioti Anastasia, Skaltsa Helen, Lazari Diamanto, Sokovic Marina, Garcia Begoña, Harvala Catherine

机构信息

Department of Pharmacognosy, School of Pharmacy, University of Athens, Panepistimiopolis, Zografou, Greece.

出版信息

Z Naturforsch C J Biosci. 2002 Jan-Feb;57(1-2):75-80. doi: 10.1515/znc-2002-1-213.

DOI:10.1515/znc-2002-1-213
PMID:11926547
Abstract

The aerial parts of Centaurea deusta Ten. afforded in addition to several known compounds, mainly sesquiterpene lactones, one new eudesmanolide and one new elemane derivative. Structures of the new compounds were elucidated by spectroscopic methods. The in vitro antifungal and antibacterial activities of the isolated compounds was tested, using the microdilution method. All compounds tested showed high antifungal activity.

摘要

十蕊矢车菊(Centaurea deusta Ten.)的地上部分除了含有几种已知化合物,主要是倍半萜内酯外,还提供了一种新的桉烷型倍半萜内酯和一种新的榄香烷衍生物。通过光谱方法阐明了新化合物的结构。使用微量稀释法测试了分离化合物的体外抗真菌和抗菌活性。所有测试化合物均显示出高抗真菌活性。

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