Ogunleye A O A, Nwaorgu G B, Grandawa Hamman
Department of Otorhinolaryngology, University College Hospital, Ibadan, Nigeria.
Trop Doct. 2002 Apr;32(2):78-80. doi: 10.1177/004947550203200206.
Ingested corrosive agents produce oropharyngeal and gastro-oesophageal injuries ranging from minor burns to severe necrosis, depending on the agent, amount, concentration and duration of exposure. A 10-year (1990-1999) study of 23 corrosive oesophagitis patients depicting the clinical spectrums and implications was done. There were 17 (74%) males and 6 (26%) females, with an average age of 16 years: 35% were in the first decade of life and 39% in the second, with an average occurrence of three new cases a year. The main corrosive agents were alkali (NaOH) 48% and sulphuric acid 39%. The factors that predisposed to corrosive ingestion included: accidental 43%; suicidal 35%; homicidal 13% and 'therapy' 9%. Of the accidental cases 60% were seen in children; 75% of suicide attempts were in the second decade of life. Eleven (48%) patients developed complications, namely laryngeal stenosis 4% and oesophageal strictures 44%. The hospital stay ranged from 2-4 weeks. Awareness of the dangers of corrosive ingestion should be extensively publicized. Government regulations permitting the sales and procurement of corrosive substances should be strictly enforced and, if not yet in place, should be enacted without further delay.
摄入腐蚀性物质会导致口咽和胃食管损伤,损伤程度从轻微烧伤到严重坏死不等,这取决于腐蚀剂的种类、摄入量、浓度以及接触时间。对23例腐蚀性食管炎患者进行了一项为期10年(1990 - 1999年)的研究,以描述其临床特征及影响。其中男性17例(74%),女性6例(26%),平均年龄16岁:35%的患者年龄在10岁以下,39%在第二个十年,平均每年新增3例病例。主要的腐蚀性物质为碱(氢氧化钠),占48%,硫酸占39%。导致腐蚀性物质摄入的因素包括:意外摄入占43%;自杀占35%;他杀占13%;“治疗性”占9%。在意外摄入病例中,60%为儿童;75%的自杀未遂者年龄在第二个十年。11例(48%)患者出现了并发症,即喉狭窄占4%,食管狭窄占44%。住院时间为2 - 4周。应广泛宣传腐蚀性物质摄入的危险性。政府关于允许销售和采购腐蚀性物质的法规应严格执行,如尚未制定,应立即颁布,不得再拖延。