Department of Surgical Sciences, University of Parma, Via Gramsci 14, 43100, Parma, Italy.
Bull World Health Organ. 2009 Dec;87(12):950-4. doi: 10.2471/BLT.08.058065.
An unsafe environment is a risk factor for child injury and violence. Among those injuries that are caused by an unsafe environment, the accidental ingestion of corrosive substances is significant, especially in developing countries where it is generally underreported.
To address this challenging, unmet medical need, we started a humanitarian programme in Sierra Leone. By reviewing the current literature from developing countries and our own experience in the field, we developed a flowchart for management of this clinical condition.
This injury is underreported in developing countries. Data available are heavily skewed towards well-resourced centres and do not reflect the entire reality of the condition. Late oesophageal strictures are usually severe. Parent's lack of knowledge, crowded living conditions and availability of chemicals in and around houses account for most ingestions. The widespread lack of any preventive measures represents the strongest risk factor.
Timely admission was observed in 19.5% of 148 patients studied. A gastrostomy was performed on 62.1% of patients, 42.8% had recurrent strictures and 19% are still on a continuous dilatation programme. Perforation and death rate were respectively 5.6% and 4%.
The majority of oesophageal caustic strictures in children are observed late, when dilatation procedures are likely to be more difficult and carry a significantly higher recurrence rate. Gastrostomy is necessary to maintain adequate nutritional status but mothers need training in feeding techniques. Both improvement in nutritional status and sustained oesophageal patency should be the reference points to a successful dilatation.
不安全的环境是儿童受伤和暴力的风险因素。在由不安全环境引起的伤害中,意外摄入腐蚀性物质的情况很严重,尤其是在发展中国家,这种情况通常报道不足。
为了解决这一具有挑战性且未得到满足的医疗需求,我们在塞拉利昂启动了一个人道主义项目。通过审查来自发展中国家的现有文献以及我们在该领域的自身经验,我们为这种临床情况的管理制定了一个流程图。
这种伤害在发展中国家报道不足。现有的数据严重偏向资源充足的中心,无法反映这种情况的全貌。食管晚期狭窄通常很严重。父母缺乏知识、居住拥挤以及房屋内外化学品的可用性是导致大多数摄入的主要原因。缺乏任何预防措施的情况普遍存在,这是最强的风险因素。
在研究的 148 名患者中,有 19.5%的患者得到了及时入院治疗。对 62.1%的患者进行了胃造口术,42.8%的患者出现了复发性狭窄,19%的患者仍在进行持续扩张计划。穿孔和死亡率分别为 5.6%和 4%。
大多数儿童腐蚀性食管狭窄是在晚期观察到的,此时扩张程序可能更困难,并且复发率显著更高。胃造口术对于维持足够的营养状况是必要的,但母亲需要接受喂养技术培训。改善营养状况和维持食管通畅性应该是成功扩张的参考点。