Wax Adam, Yang Changhuei, Backman Vadim, Kalashnikov Maxim, Dasari Ramachandra R, Feld Michael S
G. R. Harrison Spectroscopy Laboratory, Massachusetts Institute of Technology, Cambridge 02139, USA.
J Opt Soc Am A Opt Image Sci Vis. 2002 Apr;19(4):737-44. doi: 10.1364/josaa.19.000737.
We employ a novel interferometer to measure the angular distribution of light backscattered by a turbid medium. Through comparison of the measured data with the predictions of Mie theory, we are able to determine the size of the scatterers comprising the medium with subwavelength precision. As the technique is based on low-coherence interferometry, we are able to examine the evolution of the angular distribution of scattered light as it propagates into the medium. The effects of multiple scattering as a function of penetration depth in the medium are analyzed. We also present various considerations for extending this technique to determining structural information in biological tissues, such as the effects of a distribution of particle sizes and the need to average out speckle contributions.
我们采用一种新型干涉仪来测量浑浊介质后向散射光的角分布。通过将测量数据与米氏理论的预测结果进行比较，我们能够以亚波长精度确定构成该介质的散射体的尺寸。由于该技术基于低相干干涉测量法，我们能够研究散射光在传播到介质中时角分布的演变。分析了多次散射作为介质中穿透深度函数的影响。我们还提出了将该技术扩展到确定生物组织结构信息的各种考虑因素，例如粒径分布的影响以及平均散斑贡献的必要性。
