Doerks Tobias, Huber Saskia, Buchner Erich, Bork Peer
EMBL, 69012 Heidelberg, Meyerhofstr. 1, and Max-Delbrueck-Centrum, Berlin, Germany.
Trends Biochem Sci. 2002 Apr;27(4):168-70. doi: 10.1016/s0968-0004(01)02042-4.
This article describes a novel domain, BSD, that is present in basal transcription factors, synapse-associated proteins and several hypothetical proteins. It occurs in a variety of species ranging from primal protozoan to human. The BSD domain is characterized by three predicted alpha helices, which probably form a three-helical bundle, as well as by conserved tryptophan and phenylalanine residues, located at the C terminus of the domain.
本文描述了一个新的结构域BSD，它存在于基础转录因子、突触相关蛋白和几种假定蛋白中。它存在于从原始原生动物到人类的多种物种中。BSD结构域的特征是有三个预测的α螺旋，它们可能形成一个三螺旋束，以及位于该结构域C末端的保守色氨酸和苯丙氨酸残基。
