Schneider Jens P, Schulz Thomas, Horn Lars C, Leinung Steffen, Schmidt Frank, Kahn Thomas
Department of Diagnostic Radiology, University of Leipzig, Leipzig, Germany.
J Magn Reson Imaging. 2002 Apr;15(4):374-85. doi: 10.1002/jmri.10088.
The growing use of highly sensitive but only moderate specific breast MRI requires the development of both minimal-invasive as well as precise biopsy systems. The aim of the study was to prove the accuracy and feasibility of a biopsy procedure carried out in prone position in a vertically opened MR imager.
The biopsies were carried out in 21 women with lesions visible on MRI alone using an open breast coil with an integrated biopsy device. A 14 G coaxial needle was placed under near real-time MRI-guidance. After the tip of this needle was verified in contact with the lesion, we used a non MR-compatible, but MR-safe biopsy gun with a 16 G canula to take four to eight cores.
We found eight malignant and 12 benign lesions. In one patient the procedure was not successful. In case of malignancy, the operation confirmed the diagnosis in all cases. The 12/21 patients with benign lesions have been followed without evidence of lesions growth over eight to 28 months.
The described procedure allows MRI-guided minimal invasive core biopsy of small breast lesions (five to 17 mm) with a high degree of accuracy.
高灵敏度但特异性仅为中等的乳腺磁共振成像(MRI)的使用日益增加,这需要开发微创且精确的活检系统。本研究的目的是证明在垂直打开的磁共振成像仪中俯卧位进行活检程序的准确性和可行性。
对21名仅在MRI上可见病变的女性进行活检,使用带有集成活检装置的开放式乳腺线圈。在近实时MRI引导下放置一根14G同轴针。在确认该针的尖端与病变接触后,我们使用一支16G套管的非MR兼容但MR安全的活检枪获取4至8条组织芯。
我们发现8个恶性病变和12个良性病变。1例患者手术未成功。对于恶性病变,手术在所有病例中均证实了诊断。12例良性病变患者(共21例)在8至28个月的随访中未发现病变生长迹象。
所述程序可实现MRI引导下对小乳腺病变(5至17毫米)进行微创芯针活检,且具有高度准确性。