• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Live and deceased donor kidney transplantation in patients aged 75 years and older in the United States.

作者信息

Macrae Jeanne, Friedman Amy L, Friedman Eli A, Eggers Paul

机构信息

Department of Medicine, Downstate Medical Center, New York 11203, USA.

出版信息

Int Urol Nephrol. 2005;37(3):641-8. doi: 10.1007/s11255-004-0010-6.

DOI:10.1007/s11255-004-0010-6
PMID:16307355
Abstract

OBJECTIVE

To examine the outcomes of geriatric ESRD patients selected for kidney transplantation.

DESIGN

Data were extracted from the USRDS Standard Analysis Files (SAF). All persons ages 75 and over who received a kidney transplant from 1994 to 2000 were compared with those remaining on dialysis or on a transplant waiting list. Data on mortality or removal from the waiting list were obtained from the United Network for Organ Sharing (UNOS). The main outcome measure was patient and kidney transplant survival.

RESULTS

Superior five year survival after kidney transplantation was attained by the geriatric cohort given a live donor transplant (59.9%), compared with recipients of deceased donor kidneys (40.3%), dialysis patients waiting for transplant (29.7%), and those who were not selected for kidney transplantation and remained on dialysis (12.5%). The likelihood of being removed from the waiting list for any reason was higher in this group (over 75) (30.3%) than in the 66-75 age group (26.8%). Their average annual mortality rate on the waiting list was 7.9, compared to 6.6% for those 66-75.

CONCLUSION

Even after the age of 75 years, kidney transplantation provides substantial life prolongation and excellent graft survival.

摘要

相似文献

1
Live and deceased donor kidney transplantation in patients aged 75 years and older in the United States.
Int Urol Nephrol. 2005;37(3):641-8. doi: 10.1007/s11255-004-0010-6.
2
Association Between Declined Offers of Deceased Donor Kidney Allograft and Outcomes in Kidney Transplant Candidates.接受或拒绝已故供体肾移植与肾移植候选人结局的关系。
JAMA Netw Open. 2019 Aug 2;2(8):e1910312. doi: 10.1001/jamanetworkopen.2019.10312.
3
Delays in Prior Living Kidney Donors Receiving Priority on the Transplant Waiting List.既往活体肾供体在移植等待名单上获得优先排序的延迟情况。
Clin J Am Soc Nephrol. 2016 Nov 7;11(11):2047-2052. doi: 10.2215/CJN.01360216. Epub 2016 Sep 2.
4
The OPTN/UNOS Renal Transplant Registry.器官获取与移植网络/美国器官共享联合网络肾脏移植登记处
Clin Transpl. 2005:1-16.
5
Increasing the supply of kidneys for transplantation.增加用于移植的肾脏供应。
Semin Dial. 2005 Nov-Dec;18(6):460-2. doi: 10.1111/j.1525-139X.2005.00089.x.
6
Living donor kidney versus simultaneous pancreas-kidney transplant in type I diabetics: an analysis of the OPTN/UNOS database.活体供肾与 I 型糖尿病患者同期胰肾联合移植:OPTN/UNOS 数据库分析
Clin J Am Soc Nephrol. 2009 Apr;4(4):845-52. doi: 10.2215/CJN.02250508. Epub 2009 Feb 6.
7
The UNOS Renal Transplant Registry: Review of the Last Decade.美国器官共享联合网络肾脏移植登记处:过去十年回顾
Clin Transpl. 2014:1-12.
8
Association between kidney transplant center performance and the survival benefit of transplantation versus dialysis.肾移植中心的表现与移植相对于透析的生存获益之间的关联。
Clin J Am Soc Nephrol. 2014 Oct 7;9(10):1773-80. doi: 10.2215/CJN.02380314. Epub 2014 Sep 18.
9
Access to Kidney Transplantation among HIV-Infected Waitlist Candidates.HIV感染的等待名单候选人获得肾脏移植的情况。
Clin J Am Soc Nephrol. 2017 Mar 7;12(3):467-475. doi: 10.2215/CJN.07460716. Epub 2017 Feb 23.
10
Age and the associations of living donor and expanded criteria donor kidneys with kidney transplant outcomes.年龄与活体供肾和扩大标准供肾与肾移植结局的关系。
Am J Kidney Dis. 2012 Jun;59(6):841-8. doi: 10.1053/j.ajkd.2011.12.014. Epub 2012 Feb 4.

引用本文的文献

1
Senescence-induced p21 macrophages contributed to CD8 T cells-related immune hyporesponsiveness in kidney transplantation via Zfp36/IL-27 axis.衰老诱导的p21巨噬细胞通过Zfp36/IL-27轴导致肾移植中CD8 T细胞相关的免疫低反应性。
Cell Discov. 2025 Apr 15;11(1):38. doi: 10.1038/s41421-025-00784-2.
2
Kidney Transplant Outcomes in Elderly Population: A Systematic Review and Meta-analysis.老年人群肾移植结果:系统评价与荟萃分析
Eur Urol Open Sci. 2023 Mar 22;51:13-25. doi: 10.1016/j.euros.2023.02.011. eCollection 2023 May.
3
Older Age is Associated With Lower Utilization of Living Donor Kidney Transplant.

本文引用的文献

1
Renal transplant recipients over aged 60 have diminished immune activity and a low risk of rejection.60岁以上的肾移植受者免疫活性降低,排斥风险较低。
Int Urol Nephrol. 2004;36(3):451-6. doi: 10.1007/s11255-004-8685-2.
2
Patient and graft survival in older kidney transplant recipients: does age matter?老年肾移植受者的患者及移植物存活率:年龄有影响吗?
J Am Soc Nephrol. 2004 Apr;15(4):1052-60. doi: 10.1097/01.asn.0000120370.35927.40.
3
The epidemic of aging in renal replacement therapy: an update on elderly patients and their outcomes.
年龄较大与活体供肾移植的利用率较低有关。
Kidney Int Rep. 2022 Nov 13;8(2):282-293. doi: 10.1016/j.ekir.2022.11.002. eCollection 2023 Feb.
4
Comparative survival of elderly renal transplant recipients with a living donor versus a deceased donor: A retrospective single center observational study.老年肾移植受者与活体供者和尸体供者相比的生存比较:一项回顾性单中心观察研究。
Transpl Int. 2021 Dec;34(12):2746-2754. doi: 10.1111/tri.14130. Epub 2021 Oct 28.
5
The ageing kidney: Molecular mechanisms and clinical implications.衰老的肾脏:分子机制与临床意义。
Ageing Res Rev. 2020 Nov;63:101151. doi: 10.1016/j.arr.2020.101151. Epub 2020 Aug 22.
6
Frailty and Sarcopenia in Older Patients Receiving Kidney Transplantation.接受肾移植的老年患者的衰弱和肌肉减少症
Front Nutr. 2019 Nov 12;6:169. doi: 10.3389/fnut.2019.00169. eCollection 2019.
7
Characterizing the pharmacokinetics and pharmacodynamics of immunosuppressant medicines and patient outcomes in elderly renal transplant patients.描述老年肾移植患者免疫抑制药物的药代动力学和药效学以及患者预后。
Transl Androl Urol. 2019 May;8(Suppl 2):S198-S213. doi: 10.21037/tau.2018.10.16.
8
Factors affecting willingness to receive a kidney transplant among hemodialysis patients in West China: A cross-sectional survey.影响中国西部血液透析患者接受肾移植意愿的因素:一项横断面调查。
Medicine (Baltimore). 2017 May;96(18):e6722. doi: 10.1097/MD.0000000000006722.
9
Should patients older than 65 years be offered a second kidney transplant?65岁以上的患者应该接受第二次肾移植吗?
BMC Nephrol. 2017 Jan 11;18(1):13. doi: 10.1186/s12882-016-0426-0.
10
Strategies for an Expanded Use of Kidneys From Elderly Donors.扩大使用老年供体肾脏的策略。
Transplantation. 2017 Apr;101(4):727-745. doi: 10.1097/TP.0000000000001635.
肾脏替代治疗中的老龄化流行:老年患者及其治疗结果的最新情况。
Clin Nephrol. 2003 Nov;60(5):352-60. doi: 10.5414/cnp60352.
4
Old-for-old kidney allocation allows successful expansion of the donor and recipient pool.老年供肾分配有助于成功扩大供体和受体库。
Am J Transplant. 2003 Nov;3(11):1434-9. doi: 10.1046/j.1600-6135.2003.00251.x.
5
Kidney transplantation in the elderly: a decision analysis.老年人肾移植:一项决策分析。
J Am Soc Nephrol. 2003 Jan;14(1):187-96. doi: 10.1097/01.asn.0000042166.70351.57.
6
The dual kidney transplant registry.双肾移植登记处。
Clin Transpl. 2001:107-11.
7
Taking organs from the young to give to the old: is this acceptable?从年轻人身上摘取器官给老年人:这能被接受吗?
Transplantation. 2002 Aug 15;74(3):416. doi: 10.1097/00007890-200208150-00023.
8
Kidney transplantation in older patients: benefits and risks.老年患者的肾移植:益处与风险
Drugs Aging. 2002;19(2):79-84. doi: 10.2165/00002512-200219020-00001.
9
Is the loss of health-related quality of life during renal replacement therapy lower in elderly patients than in younger patients?老年患者在肾脏替代治疗期间与健康相关的生活质量损失是否低于年轻患者?
Nephrol Dial Transplant. 2001 Aug;16(8):1675-80. doi: 10.1093/ndt/16.8.1675.
10
Renal transplantation in the elderly.老年人肾移植
Int Urol Nephrol. 2000;32(2):193-201. doi: 10.1023/a:1007122322571.