来自台湾杉木木材的半日花烷型二萜类化合物。

Labdane-type diterpenoids from the wood of Cunninghamia konishii.

作者信息

Li Yen-Cheng, Kuo Yueh-Hsiung

机构信息

Department of Chemistry, National Taiwan University, Taipei, Republic of China.

出版信息

Chem Pharm Bull (Tokyo). 2002 Apr;50(4):498-500. doi: 10.1248/cpb.50.498.

DOI:10.1248/cpb.50.498

PMID:11963997

Abstract

Five new labdane-type diterpenes, 12beta,19-dihydroxymanoyl oxide (1), 8(17),13-labdadien-12,15-olid-19-oic acid (2), 12,15-epoxy-8(17),13-labdadien-18-oic acid (3), 8alpha-hydroxy-11E,13Z-labdadien-15-al (4), and (13R)-13-hydroxy-8(17), 11E,14-labdatrien-18-oic acid (5) were isolated from the wood of Cunninghamia konishii. Their structures were elucidated by two-dimensional NMR spectroscopy.

摘要

从台湾杉木木材中分离出5种新的贝壳杉烷型二萜，分别为12β,19 - 二羟基氧化半日花烷（1）、8(17),13 - 贝壳杉二烯 - 12,15 - 内酯 - 19 - 酸（2）、12,15 - 环氧 - 8(17),13 - 贝壳杉二烯 - 18 - 酸（3）、8α - 羟基 - 11E,13Z - 贝壳杉二烯 - 15 - 醛（4）和(13R) - 13 - 羟基 - 8(17),11E,14 - 贝壳杉三烯 - 18 - 酸（5）。通过二维核磁共振光谱对它们的结构进行了阐明。