Clinical experience using intraamniotic prostaglandin F2alpha for midtrimester abortion in 600 patients.

Six hundred consecutive patients received intraamniotic prostaglandin F2alpha to induce midtrimester abortion. The PGF2alpha was administered by a general population of gynecologists according to a standard protocol. The aim of the study was to observe whether results would be similar to those reported in various research studies. Of 600 abortions, 460 were complete, 140 were incomplete, and there were no abortion failures. Other parameters were also similar to previous research results, indicating that PGF2alpha can be an effective and safe means of inducing midtrimester abortion when administered by the practicing gynecologist.