Cincotta M, Borgheresi A, Boffi P, Vigliano P, Ragazzoni A, Zaccara G, Ziemann U
Unit of Neurology, Santa Maria Nuova Hospital, Florence, Italy.
Neurology. 2002 Apr 23;58(8):1290-3. doi: 10.1212/wnl.58.8.1290.
In congenital mirror movements (MM), it is unclear whether the "mirror" motor cortex (M1) produces output during intended unimanual movements. In two patients with MM, the cortical silent period (CSP) was abnormally short after focal transcranial magnetic stimulation (TMS) of either M1, but simultaneous bilateral TMS led to significant CSP lengthening. Thus, it is likely that the shortened CSP after unilateral TMS is caused by output from the nonstimulated M1, suggesting that both M1 produce output with intended unimanual movements in patients with MM.
在先天性镜像运动（MM）中，尚不清楚“镜像”运动皮层（M1）在预期的单手运动过程中是否产生输出。在两名MM患者中，对任一M1进行局灶性经颅磁刺激（TMS）后，皮层静息期（CSP）异常缩短，但同时进行双侧TMS会导致CSP显著延长。因此，单侧TMS后CSP缩短可能是由未受刺激的M1输出引起的，这表明在MM患者中，两个M1在预期的单手运动时都会产生输出。
